Gene: MOB3A
Official Full Name: MOB kinase activator 3Aprovided by HGNC
Gene Summary: Predicted to enable protein kinase activator activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27365 | MOB3A Knockout cell line (HeLa) | Human | MOB3A | 1:3~1:6 | Negative | Online Inquiry |
KO27366 | MOB3A Knockout cell line (HCT 116) | Human | MOB3A | 1:2~1:4 | Negative | Online Inquiry |
KO27367 | MOB3A Knockout cell line (HEK293) | Human | MOB3A | 1:3~1:6 | Negative | Online Inquiry |
KO27368 | MOB3A Knockout cell line (A549) | Human | MOB3A | 1:3~1:4 | Negative | Online Inquiry |
MOB3A Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically disrupt the MOB3A gene, which is implicated in various cellular processes including apoptosis, cell cycle regulation, and signal transduction pathways. The knockout mechanism is achieved through CRISPR/Cas9 technology, leading to a targeted double-strand break in the MOB3A gene, and enabling subsequent non-homologous end joining that results in frameshift mutations. This precision provides researchers with an invaluable tool for studying the functional role of the MOB3A gene in cellular physiology and pathology.
The primary function of these cell lines is to facilitate the investigation of gene function, allowing scientists to explore the biological consequences of MOB3A depletion. As a pivotal player in the Hippo signaling pathway, which governs organ size and suppresses tumorigenesis, understanding MOB3A could elucidate critical mechanisms of cancer biology, developmental disorders, and regenerative medicine.
The scientific significance of MOB3A Gene Knockout Cell Lines extends into both research and clinical domains, enabling comprehensive studies on cancer therapy responses and potential biomarkers. Researchers can utilize these models to test drug efficacy, identify novel therapeutic targets, and conduct high-throughput screening for drug discovery, thus enhancing the translation of fundamental research into clinical applications.
One major advantage of these cell lines is their reliability and reproducibility across experiments, coupled with characterized phenotypic alterations compared to standard cell lines. Our expertly designed knockout model represents a state-of-the-art alternative to traditional silencing methods, offering specificity and ease of integration into common research protocols.
By incorporating MOB3A Gene Knockout Cell Lines into your research toolkit, you empower your studies with cutting-edge genetic manipulation capabilities. This product not only aids in advancing our understanding of complex biological systems but also equips you with the tools necessary to drive innovations in therapeutic development.
Our company is committed to providing high-quality biological products, underpinned by extensive expertise in gene editing technologies and synthetic biology, ensuring that our offerings remain at the forefront of scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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