Gene: MMP21
Official Full Name: matrix metallopeptidase 21provided by HGNC
Gene Summary: This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and tumor metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30394 | MMP21 Knockout cell line (HCT 116) | Human | MMP21 | 1:2~1:4 | Negative | Online Inquiry |
MMP21 Gene Knockout Cell Lines are genetically engineered cell models designed to specifically disrupt the expression of the Matrix Metalloproteinase 21 (MMP21) gene. MMP21 is known to play a pivotal role in extracellular matrix remodeling and is implicated in various physiological and pathological processes, including tissue repair, inflammation, and cancer progression. These knockout cell lines allow researchers to study the functional consequences of MMP21 deficiency and to elucidate its involvement in cellular mechanisms, providing a powerful tool for both fundamental and applied research.
The primary function of MMP21 is to mediate the degradation of extracellular matrix components, which is critical in numerous biological processes such as wound healing and cellular migration. The knockout of this gene effectively leads to altered cell behavior, enabling researchers to investigate pathways related to extracellular matrix dynamics and related cellular activities. This mechanism of action highlights the functional diversity and biological significance of MMP21 and establishes these cell lines as valuable resources for studying its role in disease models.
In a variety of research contexts, MMP21 Gene Knockout Cell Lines have significant applications, especially in cancer biology and regenerative medicine. They facilitate the investigation of tumor microenvironment interactions as well as cellular responses to therapy, offering insights that could lead to novel treatment strategies. Clinicians and researchers can leverage these models to explore the therapeutic potential of targeting MMP21 and its associated pathways, potentially advancing personalized medicine approaches.
What sets MMP21 Gene Knockout Cell Lines apart from alternative models is their specificity in gene disruption and the reliable reproducibility of results. Compared to traditional methods, our cell lines provide a more refined and controlled system for experimentation, minimizing off-target effects and enhancing data accuracy. Moreover, these knockout models are compatible with a range of experimental techniques, making them versatile for any lab setting.
Investing in MMP21 Gene Knockout Cell Lines provides researchers and clinicians with the ability to advance their studies in matrix biology and its associated diseases, ultimately contributing to the development of innovative therapeutic approaches. Our company stands at the forefront of biotechnological advancements, dedicated to delivering high-quality biological products that empower scientific inquiry and enhance clinical outcomes in the ever-evolving landscape of biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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