Gene: MIPOL1
Official Full Name: mirror-image polydactyly 1provided by HGNC
Gene Summary: This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24071 | MIPOL1 Knockout cell line (HeLa) | Human | MIPOL1 | 1:3~1:6 | Negative | Online Inquiry |
KO24072 | MIPOL1 Knockout cell line (HCT 116) | Human | MIPOL1 | 1:2~1:4 | Negative | Online Inquiry |
KO24073 | MIPOL1 Knockout cell line (HEK293) | Human | MIPOL1 | 1:3~1:6 | Negative | Online Inquiry |
KO24074 | MIPOL1 Knockout cell line (A549) | Human | MIPOL1 | 1:3~1:4 | Negative | Online Inquiry |
MIPOL1 Gene Knockout Cell Lines are specially engineered cell lines in which the MIPOL1 gene has been inactivated, enabling researchers to study the functional consequences of gene loss. The MIPOL1 (Methylation-Induced Protein Of Leucine-rich Repeat containing 1) gene is believed to play a significant role in maintaining cellular homeostasis and regulating cellular responses to stress. By creating knockout models, scientists can investigate the gene's involvement in various biological processes, including cellular proliferation, differentiation, and apoptosis.
These cell lines operate through the principles of gene editing technologies, such as CRISPR/Cas9, which precisely target and delete the MIPOL1 coding sequence. The resulting knockout phenotype allows for the elucidation of the gene's functional role within complex biological pathways, thereby enhancing our understanding of cellular mechanisms in both normal physiology and disease states.
The scientific importance of MIPOL1 Gene Knockout Cell Lines extends into multiple research fields, including cancer biology, developmental biology, and neurobiology. Researchers can use these tools in clinical studies to investigate the potential link between MIPOL1 dysregulation and various disorders. The ability to create a model of gene inactivation provides a high degree of insight into therapeutic targets, advancing drug development and precision medicine approaches.
Compared to alternative models, such as knockdown approaches or wild-type cell lines, MIPOL1 Gene Knockout Cell Lines offer a definitive method for analyzing gene function, eliminating residual activity that can confound experimental results. This specificity allows for more robust data, increasing the reliability of findings and their potential applications.
For researchers and clinicians focused on elucidating the role of specific genes in health and disease, the MIPOL1 Gene Knockout Cell Lines are invaluable resources that facilitate innovative discoveries. With a commitment to excellence in genetic engineering, our company leverages state-of-the-art technology to deliver high-quality biological products tailored for cutting-edge scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
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