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MIB2 Knockout Cell Lines

Gene: MIB2

Official Full Name: MIB E3 ubiquitin protein ligase 2provided by HGNC

Gene Summary: The protein encoded by this gene is an E3 ubiquitin protein ligase that mediates ubiquitination of proteins in the Notch signaling pathway. The encoded protein may be a suppressor of melanoma invasion. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24789 MIB2 Knockout cell line (HeLa) Human MIB2 1:3~1:6 Negative Online Inquiry
KO24790 MIB2 Knockout cell line (HCT 116) Human MIB2 1:2~1:4 Negative Online Inquiry
KO24791 MIB2 Knockout cell line (HEK293) Human MIB2 1:3~1:6 Negative Online Inquiry
KO24792 MIB2 Knockout cell line (A549) Human MIB2 1:3~1:4 Negative Online Inquiry

Background

MIB2 Gene Knockout Cell Lines are a sophisticated biological tool created through precise genomic editing techniques, specifically designed to enable the comprehensive study of the MIB2 gene's role in various cellular processes. These cell lines have undergone targeted gene knockout, resulting in the complete disruption of MIB2 expression, facilitating research into the gene's functions, related pathways, and implications in disease states.

The MIB2 gene encodes an E3 ubiquitin ligase that plays a pivotal role in regulating protein degradation and has been implicated in several critical cellular processes, including cell cycle progression, differentiation, and signal transduction. By utilizing these knockout cell lines, researchers can investigate the downstream effects of MIB2 deletion, gaining insights into how its absence influences cellular behavior, gene expression profiles, and potential contributions to pathophysiological conditions like cancer or neurodegenerative diseases.

In scientific research and clinical settings, MIB2 Gene Knockout Cell Lines serve as an invaluable resource for drug development and therapeutic interventions, allowing for the identification of novel drug targets and elucidating mechanisms of action. Their application spans various fields, from molecular biology to pharmacology, making them crucial for understanding complex biological systems and disease mechanisms.

What sets our MIB2 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability. Each cell line is rigorously validated for knockout efficiency and cellular phenotype, ensuring reproducibility and consistency in experimental outcomes. Moreover, compared to transient knockdown approaches that may show variable results, these stable knockout lines provide a permanent and robust model conducive to long-term studies.

For researchers, clinicians, and biopharmaceutical companies, investing in MIB2 Gene Knockout Cell Lines translates to significant advancements in understanding gene function and disease mechanisms, ultimately accelerating the path from bench to bedside. With a proven track record in gene editing technology and a commitment to quality, our company is dedicated to supporting scientific discovery and innovation through superior biological products that meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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