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MIA3 Knockout Cell Lines

Gene: MIA3

Official Full Name: MIA SH3 domain ER export factor 3provided by HGNC

Gene Summary: Enables cargo receptor activity. Involved in several processes, including COPII-coated vesicle cargo loading; cell migration involved in sprouting angiogenesis; and regulation of leukocyte migration. Located in endoplasmic reticulum exit site and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20206 MIA3 Knockout cell line (HeLa) Human MIA3 1:3~1:6 Negative Online Inquiry
KO20207 MIA3 Knockout cell line (HCT 116) Human MIA3 1:2~1:4 Negative Online Inquiry
KO20208 MIA3 Knockout cell line (HEK293) Human MIA3 1:3~1:6 Negative Online Inquiry
KO20209 MIA3 Knockout cell line (A549) Human MIA3 1:3~1:4 Negative Online Inquiry

Background

MIA3 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the function of the MIA3 gene—an important component in various cellular processes, including protein trafficking and secretion. These knockout cell lines are generated using advanced CRISPR/Cas9 technology, which allows for precise, targeted modifications in the genome. By effectively disrupting the MIA3 gene, these cell lines facilitate the investigation of the gene’s role in disease mechanisms and cellular behavior.

The key function of MIA3 Gene Knockout Cell Lines lies in their ability to provide insight into the downstream effects of MIA3 disruption. Researchers can evaluate changes in cellular processes such as protein secretion, endosomal transport, and overall cell viability. The high reproducibility of these results makes them essential for understanding the broader implications of MIA3-related dysregulation in pathological conditions, including cancer and neurodegenerative diseases.

In both research and clinical settings, these cell lines present invaluable tools for elucidating the functional consequences of gene loss. They can be utilized in drug discovery initiatives, enabling the identification of potential therapeutic targets, as well as in biomarker validation studies, aiding in the development of diagnostic assays. Compared to standard cell lines, MIA3 knockout cells offer a unique advantage through their specific focus on the gene’s role, leading to more accurate and relevant insights into its biological significance.

For researchers and clinicians, the value of MIA3 Gene Knockout Cell Lines is evident; they represent a frontier in genetic research, empowering users to uncover novel findings that directly address critical questions in molecular biology and medicine. Our company, with its extensive expertise in the development of high-quality genetic cell lines, is committed to supporting the scientific community with innovative tools that foster breakthroughs in research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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