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MGARP Knockout Cell Lines

Gene: MGARP

Official Full Name: mitochondria localized glutamic acid rich proteinprovided by HGNC

Gene Summary: Predicted to be involved in several processes, including axonal transport; cellular response to gonadotropin-releasing hormone; and nervous system development. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24691 MGARP Knockout cell line (HEK293) Human MGARP 1:3~1:6 Negative Online Inquiry
KO24692 MGARP Knockout cell line (A549) Human MGARP 1:3~1:4 Negative Online Inquiry

Background

MGARP Gene Knockout Cell Lines are precisely engineered cellular models that have undergone targeted gene disruption of the multinucleate giant cells associated with muscle repair, specifically the MGARP gene. This innovative product allows researchers to investigate the gene's role in cellular processes related to muscle regeneration and pathology. By effectively knocking out the MGARP gene, these cell lines provide a unique platform to study mechanisms underlying muscle diseases, as well as potential therapeutic interventions.

The principal function of the MGARP Gene Knockout Cell Lines lies in their ability to mimic disease states by altering specific molecular pathways associated with muscle cell differentiation and regeneration. Utilizing advanced CRISPR-Cas9 technology, each knockout cell line exhibits a reliable gene disruption profile, facilitating the analysis of the gene’s function and its impact on cellular behavior. This targeted approach not only ensures high specificity but also provides insights into compensatory mechanisms in muscle cell physiology.

The scientific importance of these cell lines is underscored by their broad applicability in both basic research and clinical settings. They are invaluable for investigating myopathies, gene therapy strategies, and potential treatments for musculoskeletal disorders. Researchers can utilize these cell lines to test drug efficacy, elucidate disease mechanisms, and develop novel therapeutic approaches, ensuring the advancement of muscle biology knowledge.

Compared to other available cell lines or genetic manipulation methods, MGARP Gene Knockout Cell Lines offer significant advantages. The precise nature of the knockout, combined with high reproducibility, allows for consistent experimental outcomes. Additionally, they provide an easy-to-use platform that integrates well with high-throughput screening applications, pushing the boundaries of muscle-related research.

Ultimately, MGARP Gene Knockout Cell Lines represent a pivotal resource for scientists, enabling them to unravel the complexities of muscle biology. Our company's expertise in cutting-edge genetic engineering ensures that you receive products that meet the highest standards of quality and reliability, empowering researchers and clinicians alike in their quest for scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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