Gene: MCEE
Official Full Name: methylmalonyl-CoA epimeraseprovided by HGNC
Gene Summary: The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24715 | MCEE Knockout cell line (HeLa) | Human | MCEE | 1:3~1:6 | Negative | Online Inquiry |
KO24716 | MCEE Knockout cell line (HCT 116) | Human | MCEE | 1:2~1:4 | Negative | Online Inquiry |
KO24717 | MCEE Knockout cell line (HEK293) | Human | MCEE | 1:3~1:6 | Negative | Online Inquiry |
KO24718 | MCEE Knockout cell line (A549) | Human | MCEE | 1:3~1:4 | Negative | Online Inquiry |
MCEE Gene Knockout Cell Lines are genetically modified cell lines engineered to disable the expression of the MCEE gene, which is implicated in various metabolic and cellular functions. These knockout models are crucial for studying the gene's role in vitro, allowing researchers to investigate its contribution to metabolic pathways and disease mechanisms.
The primary function of MCEE Gene Knockout Cell Lines is to provide insight into the biological effects of MCEE gene alternation. By employing CRISPR-Cas9 technology, these cell lines have been precisely edited to lack the target gene, facilitating the exploration of gene function, cellular interactions, and potential compensatory mechanisms. Researchers can engage in targeted experiments to elucidate gene dependency and assess the phenotypic implications of MCEE disruption.
The scientific importance of these cell lines extends into both fundamental research and clinical applications. They serve as powerful tools in drug discovery, helping to identify novel therapeutic targets for metabolic disorders, and play a pivotal role in functional genomics studies. Moreover, their applications are wide-ranging, encompassing cancer research, metabolic syndrome studies, and other areas where gene expression impacts cellular behavior.
Key advantages of MCEE Gene Knockout Cell Lines include their high specificity, reproducibility, and the ease of integration into high-throughput screening processes. Unlike traditional knockout models, these cell lines are prepared under controlled conditions to ensure uniformity and reliability, minimizing genetic drift. This enhances experimental accuracy and allows for better comparison of results across studies.
For researchers, clinicians, and biopharma professionals, the MCEE Gene Knockout Cell Lines represent a vital resource for unlocking molecular mechanisms and driving advancements in therapeutic strategies. Our company specializes in advanced genetic modifications and offers a suite of customizable gene knockout models to meet the evolving needs of the scientific community. Through our commitment to quality and innovation, we empower researchers to accelerate their scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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