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MBOAT7 Knockout Cell Lines

Gene: MBOAT7

Official Full Name: membrane bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7provided by HGNC

Gene Summary: This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16306 MBOAT7 Knockout cell line (HeLa) Human MBOAT7 1:3~1:6 Negative Online Inquiry
KO16307 MBOAT7 Knockout cell line (HCT 116) Human MBOAT7 1:2~1:4 Negative Online Inquiry
KO16308 MBOAT7 Knockout cell line (HEK293) Human MBOAT7 1:3~1:6 Negative Online Inquiry
KO16309 MBOAT7 Knockout cell line (A549) Human MBOAT7 1:3~1:4 Negative Online Inquiry

Background

MBOAT7 Gene Knockout Cell Lines are tailored cellular models engineered through CRISPR/Cas9 technology to facilitate the in-depth study of the MBOAT7 gene, which plays a pivotal role in phospholipid metabolism and cellular signaling pathways. By specifically disrupting the MBOAT7 gene, these knockout cell lines allow researchers to investigate the functional consequences of MBOAT7 deletion on cellular processes such as lipid biogenesis, membrane composition, and signaling cascades that may influence disease states.

The functionality of MBOAT7 Gene Knockout Cell Lines is primarily rooted in their ability to mimic gene loss-of-function scenarios. Researchers can employ these cell lines to elucidate the biochemical pathways impacted by MBOAT7, facilitating investigations into conditions such as metabolic disorders, cancer, and neurodegeneration. The potential to derive meaningful insights from these cellular models positions them as vital tools for both basic and translational research, offering a platform for drug discovery and the validation of therapeutic targets.

One of the unique selling points of MBOAT7 Gene Knockout Cell Lines is their specificity and reliability. Unlike traditional methods that may involve cumbersome manipulation or non-specific knockdown approaches, these CRISPR-engineered models provide precise gene editing, ensuring that alterations are clean and reproducible. This specificity not only enhances the validity of experimental outcomes but also paves the way for actionable insights in clinical settings.

For researchers and clinicians, these cell lines serve as an invaluable resource that can lead to breakthroughs in understanding disease mechanisms and developing targeted therapies. The ability to unravel the roles of key genes in health and disease through robust, knockout models is crucial for advancing the field of molecular biology and precision medicine.

Our company, with years of expertise in genetic engineering and cell line development, is dedicated to providing high-quality biological products that empower the scientific community. With MBOAT7 Gene Knockout Cell Lines, we aim to support innovative research that drives impactful discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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