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MBOAT2 Knockout Cell Lines

Gene: MBOAT2

Official Full Name: membrane bound glycerophospholipid O-acyltransferase 2provided by HGNC

Gene Summary: Enables 1-acylglycerophosphocholine O-acyltransferase activity; 1-acylglycerophosphoethanolamine O-acyltransferase activity; and 1-acylglycerophosphoserine O-acyltransferase activity. Involved in phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; and phosphatidylserine acyl-chain remodeling. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26662 MBOAT2 Knockout cell line (HeLa) Human MBOAT2 1:3~1:6 Negative Online Inquiry
KO26663 MBOAT2 Knockout cell line (HCT 116) Human MBOAT2 1:2~1:4 Negative Online Inquiry
KO26664 MBOAT2 Knockout cell line (HEK293) Human MBOAT2 1:3~1:6 Negative Online Inquiry
KO26665 MBOAT2 Knockout cell line (A549) Human MBOAT2 1:3~1:4 Negative Online Inquiry

Background

MBOAT2 Gene Knockout Cell Lines are specialized cellular models designed to elucidate the biological role of the MBOAT2 gene, which encodes a member of the membrane-bound O-acyltransferase family. These knockout cell lines are engineered to lack functional MBOAT2 protein, allowing researchers to study the impact of this gene on lipid metabolism, cell signaling, and disease progression in a controlled environment. The absence of MBOAT2 provides a unique avenue to investigate the gene's involvement in various pathways, thus offering insights into its potential as a therapeutic target.

The key function of MBOAT2 lies in its role in acyl transfer reactions, which modify membrane phospholipids, influencing cellular architecture and functionality. By utilizing these knockout cell lines, researchers can observe changes in lipid composition, cell proliferation, and apoptosis, thereby gaining a deeper understanding of the gene's contribution to pathophysiological conditions, such as metabolic disorders and cancer.

The scientific importance of MBOAT2 Gene Knockout Cell Lines spans both fundamental research and clinical applications. These models can reveal crucial details about gene function that may have direct implications for the development of targeted therapies. Their applications include drug discovery, understanding drug-resistance mechanisms, and evaluating the efficacy of molecules designed to modulate MBOAT2 activity.

Compared to alternative models, MBOAT2 Gene Knockout Cell Lines offer unparalleled specificity and validation of experimental results. They provide a precise tool for researchers looking to explore gene function without the interference of confounding variables often present in wild-type or less specialized cell lines. Importantly, these knockout lines are derived from well-characterized parental cell types, ensuring robustness and reproducibility in experimental outcomes.

For researchers and clinicians focused on genetic and metabolic studies, MBOAT2 Gene Knockout Cell Lines represent a valuable asset. They not only accelerate the understanding of MBOAT2-related mechanisms but also pave the way for innovative therapeutic strategies.

Our company boasts extensive expertise in the development and application of genetic models, ensuring that our MBOAT2 Gene Knockout Cell Lines are produced under stringent quality control measures. We are committed to providing researchers with reliable tools that enhance their understanding of complex biological processes and facilitate groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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