Gene: MAPK15
Official Full Name: mitogen-activated protein kinase 15provided by HGNC
Gene Summary: Enables MAP kinase activity and chromatin binding activity. Involved in several processes, including dopamine uptake; protein localization to ciliary transition zone; and regulation of organelle organization. Located in several cellular components, including Golgi apparatus; autophagosome; and microtubule organizing center. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26582 | MAPK15 Knockout cell line (HeLa) | Human | MAPK15 | 1:3~1:6 | Negative | Online Inquiry |
KO26583 | MAPK15 Knockout cell line (HCT 116) | Human | MAPK15 | 1:2~1:4 | Negative | Online Inquiry |
KO26584 | MAPK15 Knockout cell line (HEK293) | Human | MAPK15 | 1:3~1:6 | Negative | Online Inquiry |
MAPK15 Gene Knockout Cell Lines are genetically engineered cellular models in which the MAPK15 gene has been inactivated or "knocked out," allowing researchers to study the functional consequences of MAPK15 absence in a controlled environment. This gene plays a critical role in various cellular processes, including proliferation, differentiation, apoptosis, and response to stress signals. By utilizing these knockout cell lines, scientists can elucidate the specific functions of MAPK15 and its involvement in pathological conditions such as cancer, neurodegenerative diseases, and metabolic disorders.
The key function of MAPK15 is its role as a mitogen-activated protein kinase, which is a key regulator in the signal transduction pathways. These pathways are responsible for transmitting external signals to induce appropriate cellular responses. The knockout of MAPK15 leads to altered cellular responses, offering insight into how this kinase influences various biological functions and how its dysregulation may contribute to disease states. Researchers often utilize these cell lines in functional assays and drug screening methodologies to enhance understanding of MAPK15-related molecular mechanisms.
The scientific importance of MAPK15 Gene Knockout Cell Lines is underscored by their applications in both basic and applied research settings. They provide invaluable tools for studying gene function, disease modeling, and therapeutic target validation, thereby paving the way for the development of targeted therapies and innovative treatment strategies. Their usage can further accelerate the discovery of biomarkers for disease prediction and prognosis.
One significant advantage of our MAPK15 Gene Knockout Cell Lines is the high specificity and efficiency of the knockout achieved through cutting-edge CRISPR technology, making them more reliable compared to traditional knockdown approaches. These cell lines come with comprehensive documentation, including validation data and experimental recommendations, ensuring that researchers can effectively utilize them in their studies.
For researchers and clinicians focused on exploring the mechanistic role of MAPK15 in disease or advancing therapeutic interventions, our product represents an essential asset. The versatility of these cell lines provides a robust platform for innovative research, ultimately driving forward our understanding of complex biological systems.
At [Your Company Name], we pride ourselves on being leaders in the field of genetic engineering and providing high-quality biological products that meet the needs of contemporary scientific research. Our extensive experience and commitment to innovation ensure that our MAPK15 Gene Knockout Cell Lines are among the most reliable tools available, empowering researchers to unlock novel discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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