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MAGEB6B Knockout Cell Lines

Gene: MAGEB6B

Official Full Name: MAGE family member B6Bprovided by HGNC

Gene Summary: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16390 MAGEB6B Knockout cell line (HeLa) Human MAGEB6B 1:3~1:6 Negative Online Inquiry
KO16391 MAGEB6B Knockout cell line (HCT 116) Human MAGEB6B 1:2~1:4 Negative Online Inquiry
KO16392 MAGEB6B Knockout cell line (A549) Human MAGEB6B 1:3~1:4 Negative Online Inquiry

Background

MAGEB6B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function of the MAGEB6B gene, a member of the MAGE (Melanoma Antigen Gene) family involved in various cellular processes and potentially linked to tumorigenesis. By utilizing CRISPR-Cas9 gene editing technology, these cell lines have a complete knockout of the MAGEB6B gene, providing a robust model for investigating its biological significance and role in cancer pathways.

The key function of MAGEB6B Gene Knockout Cell Lines lies in their ability to elucidate the protein interactions and signaling pathways that are affected by the absence of MAGEB6B. This can be particularly relevant in cancer research, where understanding the role of tumor antigens can guide therapeutic strategies and immuno-oncology approaches. Researchers can utilize these cell lines to assess gene expression changes, functional assays, and drug responses that may reveal novel targets for cancer treatment.

The scientific importance of MAGEB6B Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, these lines can help pave the way for biomarker identification and the development of personalized medicine approaches by revealing how the loss of specific genes can alter the tumor phenotype, thereby affecting treatment outcomes.

Compared to traditional methods of studying gene function, such as overexpression or knockdown approaches, knockout cell lines provide a more definitive model to understand gene loss-of-function effects. This specificity can lead to clearer insights and more reliable data, making these cell lines an invaluable resource for researchers looking to explore cancer biology.

Researchers and clinicians will find value in MAGEB6B Gene Knockout Cell Lines due to their ability to generate reproducible results and provide a platform for high-throughput screening applications. Our company has a proven track record in gene editing technologies and cell line development, offering exceptional quality products that empower the scientific community to unlock new discoveries in disease research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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