Home / MAD2L1BP Knockout Cell Lines

MAD2L1BP Knockout Cell Lines

Gene: MAD2L1BP

Official Full Name: MAD2L1 binding proteinprovided by HGNC

Gene Summary: The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33067 MAD2L1BP Knockout cell line (HeLa) Human MAD2L1BP 1:3~1:6 Negative Online Inquiry
KO33068 MAD2L1BP Knockout cell line (HCT 116) Human MAD2L1BP 1:2~1:4 Negative Online Inquiry
KO33069 MAD2L1BP Knockout cell line (HEK293) Human MAD2L1BP 1:3~1:6 Negative Online Inquiry
KO33070 MAD2L1BP Knockout cell line (A549) Human MAD2L1BP 1:3~1:4 Negative Online Inquiry

Background

MAD2L1BP Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to lack the MAD2L1BP gene, which plays a crucial role in the regulation of cell cycle checkpoints and is implicated in various cellular processes including mitotic control and genome stability. By introducing targeted gene knockout strategies, these cell lines facilitate in-depth studies of MAD2L1BP's function in tumorigenesis, cellular response to stress, and overall cell cycle dynamics.

These cell lines operate through a mechanism that eliminates the expression of the MAD2L1BP protein, allowing researchers to observe the resulting phenotypic changes under various experimental conditions. The loss of MAD2L1BP provides insights into mechanisms of mitotic dysregulation, making it a valuable tool for understanding how altered expression of this protein may contribute to cancer progression and treatment resistance. Studies using these knockout cell lines can pave the way for discovering potential therapeutic targets and improving current treatment modalities.

The scientific importance of MAD2L1BP Gene Knockout Cell Lines is underscored by their applications in both basic and translational research settings. They are particularly beneficial for researchers seeking to elucidate the molecular underpinnings of cell cycle regulation and its relation to various diseases, including cancer. Furthermore, these cell lines provide a controlled environment for testing new drugs and therapies aimed at modulating the cell cycle.

What sets MAD2L1BP Gene Knockout Cell Lines apart from alternative models is their high specificity, reproducibility, and ease of use. The precise knockout facilitates consistent results across experiments, thus accelerating research timelines and providing robust data. Additionally, these cell lines are compatible with various experimental techniques, including high-throughput screening and CRISPR-Cas9 studies, further extending their utility in laboratories.

Investing in MAD2L1BP Gene Knockout Cell Lines is a strategic decision for researchers and clinicians who are focused on advancing the understanding of cell cycle regulation and its implications for human diseases. With our company’s expertise in developing high-quality biological products, we ensure that these cell lines are validated and provided with comprehensive support, enabling seamless integration into your research protocols.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.