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Lmod2 Knockout Cell Lines

Gene: Lmod2

Official Full Name: leiomodin 2 (cardiac)provided by MGI

Gene Summary: Predicted to enable actin monomer binding activity and tropomyosin binding activity. Involved in actin filament polymerization and sarcomere organization. Predicted to be located in actin filament; cardiac myofibril; and sarcomere. Predicted to be active in striated muscle thin filament. Predicted to colocalize with M band. Is expressed in several structures, including aorta; central nervous system; foregut; heart; and skeletal musculature. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2G. Orthologous to human LMOD2 (leiomodin 2). [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01252 Lmod2 Knockout cell line (C2C12) Mouse Lmod2 1:3~1:4 Negative Online Inquiry

Background

Lmod2 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the Lmod2 gene, renowned for its role in actin regulation and cellular architecture. These knockout cell lines are generated using advanced gene-editing techniques, such as CRISPR-Cas9, ensuring the complete disruption of the Lmod2 gene, thereby allowing researchers to illuminate its physiological functions and involvement in various cellular processes.

The key function of Lmod2 pertains to its influential role in modulating the structure and dynamics of the cytoskeleton, particularly in the context of muscle cell integrity and function. By utilizing these knockout cell lines, researchers can elucidate the mechanisms through which Lmod2 influences actin filament organization, potentially unveiling novel insights into muscle pathologies and related disorders. The knockout models serve as a powerful tool in dissecting the molecular underpinnings of diseases such as cardiomyopathy and muscular dystrophy, while also providing a platform for drug discovery and the evaluation of therapeutic interventions.

The scientific importance of Lmod2 Gene Knockout Cell Lines extends broadly across both research and clinical settings. Their usage can significantly expedite the understanding of actin-related diseases, as well as improve the development of targeted therapies. Unlike traditional cell lines or models, the specificity of the knockout approach allows for heightened accuracy in experimental outcomes—enabling scientists to draw more reliable conclusions about the role of Lmod2 in cellular physiology.

Unique selling points of these knockout cell lines include their high reproducibility, ease of use in experimental protocols, and the potential to provide groundbreaking insights with minimal resources. Researchers can employ these models in various assays, including gene expression analysis, drug response studies, and cellular migration investigations, making them versatile tools suited for a wide array of experimental setups.

The value of Lmod2 Gene Knockout Cell Lines is magnified for researchers and clinicians alike, as they pave the way for innovative approaches to understanding and treating muscle-related diseases. By providing a reliable, well-characterized platform for research, these cell lines empower scientists to make significant strides in their investigations.

Our company is dedicated to advancing the field of molecular and cellular biology through the production of high-quality biological products. With a strong background in genetic engineering and a commitment to research excellence, we continue to offer innovative solutions that support the scientific community’s quest for knowledge and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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