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LZTR1 Knockout Cell Lines

Gene: LZTR1

Official Full Name: leucine zipper like post translational regulator 1provided by HGNC

Gene Summary: This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00065 LZTR1 Knockout cell line (SNU-398) Human LZTR1 Negative Online Inquiry
KO00079 LZTR1 Knockout cell line (Hep 3B2.1-7) Human LZTR1 1:2~1:4 Negative Online Inquiry
KO04510 LZTR1 Knockout cell line (HeLa) Human LZTR1 1:3~1:6 Negative Online Inquiry
KO04511 LZTR1 Knockout cell line (HCT 116) Human LZTR1 1:2~1:4 Negative Online Inquiry
KO04512 LZTR1 Knockout cell line (HEK293) Human LZTR1 1:3~1:6 Negative Online Inquiry
KO04513 LZTR1 Knockout cell line (A549) Human LZTR1 1:3~1:4 Negative Online Inquiry

Background

LZTR1 Gene Knockout Cell Lines are genetically engineered cells in which the LZTR1 gene has been inactivated or "knocked out" through targeted genomic editing techniques such as CRISPR-Cas9. The LZTR1 gene is known to play a crucial role in various cellular processes, including regulation of different signaling pathways, cell cycle progression, and response to stress. By creating a knockout model, researchers can examine the physiological and pathological consequences of LZTR1 loss, providing insights into its function in cellular homeostasis and disease processes, including tumorigenesis.

These cell lines serve critical functions in elucidating the mechanistic roles of LZTR1 in diseases such as cancer and neurological disorders. They provide a robust platform for studying gene function, signaling pathways, and the interplay between LZTR1 and other genetic factors. This is particularly significant in cancer research, where dysregulation of LZTR1 has been implicated in various malignancies, allowing researchers to explore potential therapeutic interventions targeting LZTR1-related pathways.

The LZTR1 Gene Knockout Cell Lines offer distinct advantages over conventional models, such as whole organisms or non-targeted knockdown systems. They allow for precise investigation of gene function in a controlled environment, minimize off-target effects, and provide a more reproducible and scalable system for experiments. Furthermore, these cell lines are readily available and can be adapted to a variety of cell types and experimental conditions, enhancing their utility for diverse research applications.

For researchers and clinicians focused on genetics, cancer biology, and cellular responses, the LZTR1 Gene Knockout Cell Lines represent a valuable tool that can facilitate groundbreaking discoveries, aid in the development of targeted therapies, and expand our understanding of complex disease mechanisms. Our company has extensive expertise in developing high-quality biological products, ensuring that our knockout cell lines meet rigorous scientific standards and deliver reliable results for our users.

Please note that all services are for research use only. Not intended for any clinical use.

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