Gene: LYRM7
Official Full Name: LYR motif containing 7provided by HGNC
Gene Summary: Inner mitochondrial membrane complex III (CIII) is the main enzyme complex in the mitochondrial respiratory chain, and Rieske Fe-S protein (UQCRFS1) is the last catalytic subunit added to the complex. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defects in this gene are a cause of mitochondrial complex III deficiency, nuclear type 8. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23693 | LYRM7 Knockout cell line (HeLa) | Human | LYRM7 | 1:3~1:6 | Negative | Online Inquiry |
KO23694 | LYRM7 Knockout cell line (HCT 116) | Human | LYRM7 | 1:2~1:4 | Negative | Online Inquiry |
KO23695 | LYRM7 Knockout cell line (HEK293) | Human | LYRM7 | 1:3~1:6 | Negative | Online Inquiry |
KO23696 | LYRM7 Knockout cell line (A549) | Human | LYRM7 | 1:3~1:4 | Negative | Online Inquiry |
LYRM7 Gene Knockout Cell Lines are genetically modified cell lines where the LYRM7 gene has been specifically inactivated, enabling researchers to study the functional implications of this gene in various biological processes. These cell lines serve as a powerful tool for elucidating the role of LYRM7 in mitochondrial function, cellular metabolism, and associated signaling pathways.
The primary function of the LYRM7 Gene Knockout Cell Lines lies in their ability to facilitate targeted investigations into the biological consequences of LYRM7 gene disruption. The knockout process employs CRISPR-Cas9 technology, a widely recognized genome-editing technique, allowing efficient and precise modifications. By observing phenotypic changes, scientists can glean insights into the gene's regulatory mechanisms, interactions with other cellular components, and its impact on overall cellular health and viability.
The scientific importance of LYRM7 Gene Knockout Cell Lines encompasses a broad range of applications in both research and clinical settings. Their use can contribute significantly to the understanding of mitochondrial dysregulation in diseases such as neurodegeneration and cancer. Additionally, they provide a vital model for drug discovery and development, enabling the screening of potential therapeutic agents targeting mitochondrial dysfunction.
What sets our LYRM7 Gene Knockout Cell Lines apart from alternative products is their high specificity and reproducibility, ensuring consistent results across different experiments. Each cell line is carefully validated for the complete knockout of the LYRM7 gene, minimizing off-target effects and enhancing the trustworthiness of experimental outcomes. Moreover, our customer support provides guidance on experimental design and protocols tailored to maximizing the utility of our cell lines.
For researchers and clinicians in the field, these cell lines represent an invaluable resource for driving forward investigations into mitochondrial biology and disease. By choosing our LYRM7 Gene Knockout Cell Lines, you align your research with high-quality, dependable models that can enhance the depth and breadth of your scientific inquiries. With years of experience in producing advanced biological products, our company is committed to delivering exceptional tools that empower the scientific community's exploration of genetic and cellular functionality.
Please note that all services are for research use only. Not intended for any clinical use.
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