Gene: LUC7L
Official Full Name: LUC7 likeprovided by HGNC
Gene Summary: The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001 [PubMed 11170747]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16425 | LUC7L Knockout cell line (HeLa) | Human | LUC7L | 1:3~1:6 | Negative | Online Inquiry |
KO16426 | LUC7L Knockout cell line (HCT 116) | Human | LUC7L | 1:2~1:4 | Negative | Online Inquiry |
KO16427 | LUC7L Knockout cell line (HEK293) | Human | LUC7L | 1:3~1:6 | Negative | Online Inquiry |
KO16428 | LUC7L Knockout cell line (A549) | Human | LUC7L | 1:3~1:4 | Negative | Online Inquiry |
LUC7L Gene Knockout Cell Lines are specifically engineered cellular models designed to study the role of the LUC7L gene in various biological processes. These cell lines utilize CRISPR-Cas9 technology to create targeted disruptions in the LUC7L gene, allowing researchers to investigate its function and implications in gene expression regulation, cell differentiation, and potential links to diseases.
The primary mechanism at work in these knockout cell lines is the Cas9 endonuclease, which introduces double-strand breaks in the DNA at precise locations specified by guide RNAs. This enables the efficient disruption of the target gene, leading to a functional loss that can be analyzed in a controlled laboratory setting. Researchers can then assess the downstream effects on cellular pathways, providing insights into disease mechanisms and potential therapeutic targets.
The scientific importance of LUC7L knockout cell lines lies in their application in both research and clinical settings. They can facilitate the discovery of molecular interactions and pathways influenced by the LUC7L gene, aiding in the understanding of various conditions such as cancers, neurodegenerative diseases, and genetic disorders. Additionally, these cell lines can be utilized for drug screening and development, enabling researchers to identify compounds that can modulate the gene's activity.
A significant advantage of the LUC7L Gene Knockout Cell Lines compared to conventional models is their precision and reproducibility, which are crucial for robust experimental outcomes. Traditional gene editing methods often lead to random mutations, introducing variability that can complicate analysis. In contrast, our knockout system ensures a consistent and controlled approach to gene disruption.
For researchers, clinicians, and pharmaceutical developers, the LUC7L Gene Knockout Cell Lines represent a valuable tool for elucidating gene function and therapeutic discovery. Their use can accelerate the pace of biomedical research and enhance the potential for innovative treatment options. Our company, with its commitment to advancing genetic research tools, offers extensive expertise and a portfolio of products designed to empower scientists in their pursuit of knowledge and groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.