Gene: LTBP2
Official Full Name: latent transforming growth factor beta binding protein 2provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36763 | LTBP2 Knockout cell line (HeLa) | Human | LTBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO36764 | LTBP2 Knockout cell line (HCT 116) | Human | LTBP2 | 1:2~1:4 | Negative | Online Inquiry |
KO36765 | LTBP2 Knockout cell line (HEK293) | Human | LTBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO36766 | LTBP2 Knockout cell line (A549) | Human | LTBP2 | 1:3~1:4 | Negative | Online Inquiry |
LTBP2 Gene Knockout Cell Lines are specialized human or animal cell lines in which the latent transforming growth factor-beta-binding protein 2 (LTBP2) gene has been intentionally disrupted or "knocked out" through precise genetic engineering techniques such as CRISPR-Cas9. This innovative product is pivotal for understanding the role of LTBP2 in various biological processes, particularly those related to extracellular matrix organization, tissue homeostasis, and immune regulation.
These cell lines function as powerful tools for researchers to elucidate the molecular mechanisms underlying the physiological and pathological functions attributed to LTBP2. By studying these knockout lines, scientists can assess the effects of LTBP2 deficiency on cellular behavior, including proliferation, differentiation, and responses to growth factors. This loss-of-function model is essential for unraveling the contributions of LTBP2 in diseases such as fibrosis and certain cancers, where TGF-β signaling pathways are implicated.
The scientific importance of LTBP2 Gene Knockout Cell Lines extends to both basic and applied research. They are invaluable in drug discovery and development, enabling the screening of therapeutic agents designed to modulate TGF-β signaling pathways. In clinical settings, understanding LTBP2's function can aid in the identification of biomarkers and therapeutic targets for conditions associated with aberrant extracellular matrix remodeling.
Compared to alternative products available in the market, such as wild-type cell lines or non-targeted knockouts, our LTBP2 Gene Knockout Cell Lines provide unparalleled specificity and reliability. Researchers can conduct experiments with greater confidence, knowing that the observed effects are directly attributable to the engineered knockout of the LTBP2 gene.
For researchers and clinicians, the value of LTBP2 Gene Knockout Cell Lines lies not only in their ability to facilitate groundbreaking discoveries but also in their potential to translate findings into clinical applications. As a company committed to advancing scientific research, we pride ourselves on providing high-quality biological products that meet the rigorous standards of modern investigation. Our expertise in genetic engineering and cell line production ensures that you receive robust and reliable tools to support your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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