Gene: LRRCC1
Official Full Name: leucine rich repeat and coiled-coil centrosomal protein 1provided by HGNC
Gene Summary: This gene encodes a centrosomal protein that maintains the structural integrity of the centrosome and plays a key role in mitotic spindle formation. The encoded protein contains an N-terminal leucine-rich repeat domain and a C-terminal coiled-coil domain. It associates with the centrosome throughout the cell cycle and accumulates on the mitotic centrosome. [provided by RefSeq, Mar 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24232 | LRRCC1 Knockout cell line (HeLa) | Human | LRRCC1 | 1:3~1:6 | Negative | Online Inquiry |
KO24233 | LRRCC1 Knockout cell line (HCT 116) | Human | LRRCC1 | 1:2~1:4 | Negative | Online Inquiry |
KO24234 | LRRCC1 Knockout cell line (HEK293) | Human | LRRCC1 | 1:3~1:6 | Negative | Online Inquiry |
KO24235 | LRRCC1 Knockout cell line (A549) | Human | LRRCC1 | 1:3~1:4 | Negative | Online Inquiry |
LRRCC1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the LRRCC1 gene, which encodes a protein involved in regulating various cellular processes, including cell migration, adhesion, and response to stress. The knockout of this gene creates a cellular model that allows researchers to investigate its functional role within biological systems more effectively.
The primary function of these cell lines lies in their ability to enable precise manipulation of the genetic background in research studies, particularly in understanding the contributions of the LRRCC1 protein to various physiological and pathological conditions. By employing CRISPR/Cas9 technology, these knockout lines eliminate the coding region of the LRRCC1 gene, thereby providing a robust platform to dissect the gene’s effects on signaling pathways, cellular behavior, and molecular interactions, which can be crucial for exploring disease mechanisms such as cancer metastasis and neurodegeneration.
The scientific importance of LRRCC1 Gene Knockout Cell Lines extends to both basic research and clinical applications. They are valuable tools in drug discovery, particularly for therapeutic targeting, as they allow for the identification of new biomolecular pathways and potential intervention points. Furthermore, these cell lines can serve as models for testing the efficacy of pharmacological agents in conditions where LRRCC1 plays a critical role.
What sets these knockout cell lines apart from alternatives is their high specificity and the robust validation process that ensures complete gene disruption. This specificity leads to more reliable data, reducing the ambiguity often associated with less-targeted genetic manipulation methods. Additionally, their ease of use and adaptability into various experimental setups make them an essential asset for researchers looking to streamline their investigative processes.
Incorporating LRRCC1 Gene Knockout Cell Lines into research strategies offers valuable insights, paving the way for innovative discoveries and advancements in understanding complex biological phenomena. Our company prides itself on delivering high-quality, scientifically validated cell lines that enhance research outcomes, supported by a team of experts committed to the advancement of cellular biology and genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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