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LRIT3 Knockout Cell Lines

Gene: LRIT3

Official Full Name: leucine rich repeat, Ig-like and transmembrane domains 3provided by HGNC

Gene Summary: This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F. [provided by RefSeq, May 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16479 LRIT3 Knockout cell line (HCT 116) Human LRIT3 1:2~1:4 Negative Online Inquiry

Background

LRIT3 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the in-depth study of the LRIT3 gene, known for its role in cell signaling and development processes. Utilizing CRISPR-Cas9 gene-editing technology, these cell lines have been precisely modified to ablate the expression of the LRIT3 gene, providing researchers with a powerful tool to investigate the gene's functions and associated biological pathways.

The primary mechanism of these knockout cell lines enables scientists to examine the phenotypic consequences of loss of LRIT3 function. By systematically analyzing cell proliferation, apoptosis, and signaling pathways, researchers can elucidate the molecular networks influenced by LRIT3. This functional analysis paves the way for breakthroughs in understanding its implications in developmental biology, cancer research, and neurobiology.

In both research and clinical settings, LRIT3 Gene Knockout Cell Lines are invaluable for their capability to shed light on gene functions within pathophysiological contexts. They enable drug discovery efforts by identifying potential therapeutic targets and optimizing treatment responses. Furthermore, they construct a robust framework for high-throughput screening assays, significantly accelerating the progression from basic research to clinical applications.

What distinguishes our LRIT3 Gene Knockout Cell Lines from alternative products is the precision of our gene editing, coupled with a rigorously validated model to ensure reproducibility and reliability in experimental outcomes. Researchers can rely on our extensive characterization data that accompanies each cell line, giving them confidence in statistical robustness and enhancing the reproducibility of results.

In summary, LRIT3 Gene Knockout Cell Lines are essential for researchers seeking to further our understanding of the LRIT3 gene's role in health and disease. Our commitment to quality, innovation, and comprehensive support reflects our expertise in biological research tools, ensuring that our customers receive not just a product, but a significant advancement in their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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