Gene: LRIF1
Official Full Name: ligand dependent nuclear receptor interacting factor 1provided by HGNC
Gene Summary: Predicted to enable nuclear retinoic acid receptor binding activity. Involved in dosage compensation by inactivation of X chromosome. Located in centriolar satellite; chromosome, telomeric region; and nuclear lumen. Implicated in facioscapulohumeral muscular dystrophy 3. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16480 | LRIF1 Knockout cell line (HeLa) | Human | LRIF1 | 1:3~1:6 | Negative | Online Inquiry |
KO16481 | LRIF1 Knockout cell line (HCT 116) | Human | LRIF1 | 1:2~1:4 | Negative | Online Inquiry |
KO16482 | LRIF1 Knockout cell line (HEK293) | Human | LRIF1 | 1:3~1:6 | Negative | Online Inquiry |
KO16483 | LRIF1 Knockout cell line (A549) | Human | LRIF1 | 1:3~1:4 | Negative | Online Inquiry |
LRIF1 Gene Knockout Cell Lines are specialized biological tools designed for the precise study of the LRIF1 gene's function and its role in various cellular processes. By employing CRISPR-Cas9 technology, these cell lines have been genetically engineered to disrupt the LRIF1 gene, resulting in a knockout phenotype that allows researchers to observe the consequences of this genetic alteration on cellular behavior and signaling pathways. This functionality provides a powerful framework for understanding the gene’s involvement in critical biological processes such as cell proliferation, differentiation, and apoptosis.
The mechanisms of action of the LRIF1 Gene Knockout Cell Lines are particularly relevant in elucidating the gene's role in disease mechanisms, such as cancer and metabolic disorders. By providing a cellular context in which the normal function of LRIF1 is entirely absent, researchers can effectively delineate its contributions to specific phenotypes, gene interactions, and pathway dynamics. These knockout lines facilitate high-throughput screening, pathway analysis, and the assessment of potential drug targets, making them invaluable in both basic and applied biomedical research.
One of the most significant advantages of our LRIF1 Gene Knockout Cell Lines compared to traditional gene knockdown approaches is the permanence of the knockout, which ensures consistent results across experiments and faster definitive conclusions. Unlike transient knockdown methods that can introduce variability, our knockout cell lines provide a stable platform for long-term studies. Furthermore, they allow for direct comparisons with wild-type cells, enriching the insights gained from experimental data.
This product is exceptionally valuable to researchers and clinicians focused on genetic research, pharmacological studies, and therapeutic development. By employing these knockout cell lines, users can accelerate the discovery of new insights into gene function, aid drug screening efforts, and ultimately contribute to advancing treatment modalities for gene-associated diseases.
At our company, we pride ourselves on our expertise in genetic engineering and cell line development, offering researchers access to a robust and diverse portfolio of cellular models that empower scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.