Gene: LRFN3
Official Full Name: leucine rich repeat and fibronectin type III domain containing 3provided by HGNC
Gene Summary: Predicted to be involved in regulation of presynapse assembly; regulation of synaptic membrane adhesion; and synaptic membrane adhesion. Predicted to be located in plasma membrane. Predicted to be active in cell surface; glutamatergic synapse; and synaptic membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16484 | LRFN3 Knockout cell line (HeLa) | Human | LRFN3 | 1:3~1:6 | Negative | Online Inquiry |
KO16485 | LRFN3 Knockout cell line (HCT 116) | Human | LRFN3 | 1:2~1:4 | Negative | Online Inquiry |
KO16486 | LRFN3 Knockout cell line (HEK293) | Human | LRFN3 | 1:3~1:6 | Negative | Online Inquiry |
KO16487 | LRFN3 Knockout cell line (A549) | Human | LRFN3 | 1:3~1:4 | Negative | Online Inquiry |
LRFN3 Gene Knockout Cell Lines are specialized cellular models engineered to have a targeted deletion of the LRFN3 gene, which encodes for leucine-rich repeat and fibronectin type III domain-containing protein 3. These knockout cell lines are pivotal for dissecting the biological roles and pathways associated with LRFN3, particularly in neurodevelopment and synaptic functions. By eliminating this gene, researchers can investigate the resultant phenotypes and unveil the implications of LRFN3 expression in various physiological and pathological conditions.
The primary function of these cell lines lies in their ability to provide a controlled environment for studying gene function, cellular signaling pathways, and phenotypic changes. The knockout mechanism typically utilizes CRISPR-Cas9 technology or RNA interference, allowing for precise genetic manipulation. By analyzing these cell lines, scientists can delve into the impacts of LRFN3 loss on cell proliferation, differentiation, and responses to external stimuli, thereby enriching our understanding of its role in health and disease.
The scientific significance of LRFN3 Gene Knockout Cell Lines extends to various research fields, including neuroscience, cancer biology, and regenerative medicine. These models enable researchers to elucidate the molecular underpinnings of disorders, such as neurodegenerative diseases and certain cancers, where LRFN3 may play a crucial role, facilitating the development of targeted therapeutic strategies.
In comparison to alternative models, the LRFN3 Gene Knockout Cell Lines offer distinct advantages such as enhanced specificity of gene editing vs. traditional methods, the purity of the gene knockout, and a more accurate representation of the genetic context in cellular responses. These attributes render them invaluable tools for researchers seeking to translate basic science findings into clinical applications effectively.
For researchers and clinicians alike, the value of LRFN3 Gene Knockout Cell Lines cannot be overstated. They provide a streamlined platform for innovative research, potentially leading to breakthroughs in therapeutic interventions and biomarker discovery. Our company, dedicated to advancing biological research, boasts a robust expertise in gene editing technologies and a portfolio tailored to meet the evolving needs of the scientific community, ensuring that you have access to the most reliable and effective tools for your research objectives.
Please note that all services are for research use only. Not intended for any clinical use.
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