Gene: LIPH
Official Full Name: lipase Hprovided by HGNC
Gene Summary: This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37822 | LIPH Knockout cell line (HeLa) | Human | LIPH | 1:3~1:6 | Negative | Online Inquiry |
KO37823 | LIPH Knockout cell line (HCT 116) | Human | LIPH | 1:2~1:4 | Negative | Online Inquiry |
KO37824 | LIPH Knockout cell line (HEK293) | Human | LIPH | 1:3~1:6 | Negative | Online Inquiry |
KO37825 | LIPH Knockout cell line (A549) | Human | LIPH | 1:3~1:4 | Negative | Online Inquiry |
LIPH Gene Knockout Cell Lines are expertly developed cellular models specifically designed to study the roles and mechanisms of the Lipase H (LIPH) gene in various biological processes. LIPH encodes an enzyme that is instrumental in lipid metabolism, affecting cell signaling pathways and adipocyte function. The targeted knockout of this gene facilitates in-depth examination of its function, allowing researchers to explore its involvement in metabolic disorders, obesity, and related diseases.
These cell lines utilize advanced CRISPR-Cas9 gene-editing technology, ensuring precise and efficient disruption of the LIPH gene. As a result, researchers can observe phenotypic changes related to lipid accumulation and energy homeostasis, providing crucial insights into the molecular underpinnings of lipid metabolism. The utility of LIPH Gene Knockout Cell Lines extends from basic biological research to translational applications, such as drug discovery and development, where understanding the lipid metabolism pathway can inform therapeutic strategies for metabolic diseases.
One of the standout advantages of this product is the specificity and reproducibility it offers compared to other gene-editing methods. Unlike traditional methods that may lead to off-target effects or mosaicism, CRISPR-Cas9 provides a higher degree of accuracy, thereby enhancing experimental reliability. Moreover, the availability of these cell lines enables a wide range of assays, including metabolic profiling, gene expression analysis, and cellular signaling investigations.
For researchers and clinicians focused on obesity and metabolic conditions, LIPH Gene Knockout Cell Lines are indispensable tools that not only streamline the investigational process but also open avenues for innovative therapeutic insights. Understanding the precise role of LIPH can pave the way for targeted interventions, ultimately enhancing patient outcomes.
Our commitment to delivering high-quality, biologically relevant products is founded on rigorous scientific expertise and innovation. We strive to empower researchers with the tools they need to advance their studies in metabolic health, allowing for breakthroughs that lead to improved clinical practices and therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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