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LHX2 Knockout Cell Lines

Gene: LHX2

Official Full Name: LIM homeobox 2provided by HGNC

Gene Summary: This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33302 LHX2 Knockout cell line (HeLa) Human LHX2 1:3~1:6 Negative Online Inquiry
KO33303 LHX2 Knockout cell line (HCT 116) Human LHX2 1:2~1:4 Negative Online Inquiry
KO33304 LHX2 Knockout cell line (HEK293) Human LHX2 1:3~1:6 Negative Online Inquiry
KO33305 LHX2 Knockout cell line (A549) Human LHX2 1:3~1:4 Negative Online Inquiry

Background

LHX2 Gene Knockout Cell Lines are genetically modified cell cultures specifically engineered to lack the LHX2 gene, which encodes a transcription factor critical for various developmental processes. These cell lines serve as an essential tool for researchers studying the roles of LHX2 in neural development, pituitary function, and neurogenesis. By creating a knockout model, scientists can investigate the gene’s contributions to cellular behaviors, signaling pathways, and its implications in diseases such as pituitary adenomas or neurodegenerative disorders.

The key mechanism behind the LHX2 gene knockout involves targeted gene disruption techniques such as CRISPR/Cas9 or homologous recombination, which result in a complete loss of LHX2 expression. This functional absence allows for the dissection of the downstream effects of LHX2 deficiency, providing insights into gene interactions and compensatory mechanisms activated within the cellular environment.

In both research and clinical settings, LHX2 Gene Knockout Cell Lines have immense scientific value. They enable the investigation of gene function in a controlled environment, facilitating drug discovery and the development of therapeutic strategies targeting LHX2-related pathways. Researchers can elucidate the molecular underpinnings of related pathologies, contributing to a better understanding of disease etiology and potential interventions.

Compared to other cell lines, the unique advantage of LHX2 Gene Knockout Cell Lines lies in their specificity and the clarity they provide in studying the physiological and pathological effects of LHX2 absence. Unlike wild-type cell lines, which may obscure gene functions due to confounding variables, these knockout models offer a focused approach to understanding the targeted gene's role.

For researchers and clinicians alike, the value of LHX2 Gene Knockout Cell Lines is pronounced. They serve not only as a robust platform for basic research but also as a translational tool that can accelerate the path to clinical applications. With our company’s extensive expertise in molecular genetics and cell line development, we are committed to providing high-quality, reliable products that empower scientific progress and innovation in the understanding of gene functions and their implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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