Gene: LHFPL5
Official Full Name: LHFPL tetraspan subfamily member 5provided by HGNC
Gene Summary: This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti. It is proposed to function in hair bundle morphogenesis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27072 | LHFPL5 Knockout cell line (HeLa) | Human | LHFPL5 | 1:3~1:6 | Negative | Online Inquiry |
KO27073 | LHFPL5 Knockout cell line (HCT 116) | Human | LHFPL5 | 1:2~1:4 | Negative | Online Inquiry |
KO27074 | LHFPL5 Knockout cell line (HEK293) | Human | LHFPL5 | 1:3~1:6 | Negative | Online Inquiry |
KO27075 | LHFPL5 Knockout cell line (A549) | Human | LHFPL5 | 1:3~1:4 | Negative | Online Inquiry |
LHFPL5 Gene Knockout Cell Lines represent a significant advancement in genetic research, providing scientists with a powerful tool to investigate the functions and mechanisms associated with the LHFPL5 gene. This gene, pivotal in various cellular processes, is known to play a critical role in neuron development and synaptic function. By employing CRISPR-Cas9 technology, these knockout cell lines effectively disable the LHFPL5 gene, facilitating the study of its involvements in neurological disorders and normal physiological functions.
The primary function of LHFPL5 Gene Knockout Cell Lines lies in their ability to allow researchers to discern the pathways and interactions that the LHFPL5 protein influences. This is particularly valuable in understanding neurodegenerative diseases, where dysregulation of synaptic proteins is often implicated. Researchers can investigate cellular responses, signaling cascades, and phenotypic changes that arise within these knockout models, leading to greater insights into disease mechanisms and potential therapeutic targets.
From a scientific perspective, LHFPL5 Gene Knockout Cell Lines are invaluable in various research applications including drug discovery, gene therapy, and personalized medicine. Their ability to model human cellular environments allows for robust experimental setups that can yield high-fidelity results, distinguishing them from traditional cell lines that may not accurately represent native physiological conditions. Furthermore, the specificity of the knockout ensures that the observed effects directly correlate to the loss of LHFPL5, enhancing the reliability of experimental data.
Compared to alternatives such as RNA interference or partial gene modulation techniques, LHFPL5 Gene Knockout Cell Lines provide a more definitive approach to gene function analysis. They deliver complete disruption of the LHFPL5 gene, thereby avoiding the pitfalls of off-target effects associated with other methodologies.
For researchers and clinicians focused on neurobiology and the underlying mechanisms of neurological diseases, investing in LHFPL5 Gene Knockout Cell Lines promises to yield significant insights and advancements in their work. With a focus on rigorous scientific methods and high-quality biological products, our company is dedicated to supporting research endeavors with cutting-edge tools that accelerate discovery and innovation in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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