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LEAP2 Knockout Cell Lines

Gene: LEAP2

Official Full Name: liver enriched antimicrobial peptide 2provided by HGNC

Gene Summary: This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts. [provided by RefSeq, Sep 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00650 LEAP2 gRNA5-gRNA6 KO plasmid LEAP2 $850
KO00837 LEAP2 Knockout cell line (Huh-7) Human LEAP2 1:2~1:3 Negative Online Inquiry

Background

LEAP2 Gene Knockout Cell Lines are precisely engineered cellular models that facilitate the study of the LEAP2 gene, known for its role in regulating metabolism and appetite control. These knockout cell lines are generated using advanced CRISPR-Cas9 gene editing technology, effectively disrupting the LEAP2 gene, which allows researchers to investigate the gene's functional significance in various biological processes.

The key functionality of LEAP2 Gene Knockout Cell Lines lies in their ability to mimic the physiological effects of LEAP2 disruption in vitro. By removing this gene, researchers can assess changes in metabolic pathways, hormonal regulation, and cellular responses to nutrient availability. This enables a deeper understanding of the LEAP2 signaling mechanisms and its broader implications in conditions such as obesity, diabetes, and metabolic syndrome.

The scientific importance of LEAP2 Gene Knockout Cell Lines extends into both basic and applied research. These models are invaluable for drug discovery and development, allowing for the screening of therapeutic compounds that may target aberrant pathways associated with LEAP2. In clinical settings, insights drawn from studies utilizing these cell lines can directly inform treatment strategies for metabolic disorders, enhancing patient outcomes.

Compared to alternative models, such as wild-type cell lines or whole organism studies, LEAP2 Gene Knockout Cell Lines offer a more controlled environment for specific gene functional analysis. This specificity reduces variability and allows for high-throughput screening applications, systematically elucidating the role of LEAP2 in a way that is less feasible with traditional models.

For researchers and clinicians, the value of LEAP2 Gene Knockout Cell Lines lies in their ability to generate robust and reproducible data. These cell lines serve as a powerful tool for elucidating the complex interactions involved in metabolic regulation and disease, making them essential for advancing our understanding and treatment of metabolic disorders.

Our company specializes in developing innovative biological products designed to meet the needs of the research community. With a commitment to quality and scientific excellence, we ensure that our LEAP2 Gene Knockout Cell Lines will support groundbreaking discoveries in metabolic research.

Please note that all services are for research use only. Not intended for any clinical use.

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