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LARP1B Knockout Cell Lines

Gene: LARP1B

Official Full Name: La ribonucleoprotein 1Bprovided by HGNC

Gene Summary: This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16599 LARP1B Knockout cell line (HeLa) Human LARP1B 1:3~1:6 Negative Online Inquiry
KO16600 LARP1B Knockout cell line (HCT 116) Human LARP1B 1:2~1:4 Negative Online Inquiry
KO16601 LARP1B Knockout cell line (HEK293) Human LARP1B 1:3~1:6 Negative Online Inquiry
KO16602 LARP1B Knockout cell line (A549) Human LARP1B 1:3~1:4 Negative Online Inquiry

Background

LARP1B Gene Knockout Cell Lines are specifically engineered cell lines that feature targeted deletions of the LARP1B gene, a critical component involved in mRNA translation regulation. By utilizing CRISPR/Cas9 genomic editing techniques, these cell lines enable researchers to investigate the role of LARP1B in various cellular processes, including cell growth, differentiation, and response to environmental stress. The knockout of this gene elucidates its function in the modulation of translation efficiency and stability, thereby revealing potential signaling pathways that are influenced by LARP1B activity.

The significance of LARP1B lies in its association with crucial biological processes and diseases, including cancer. In clinical research, these knockout cell lines serve as invaluable tools for studying the implications of LARP1B in tumorigenesis and for screening therapeutic responses to novel treatment strategies. The ability to observe changes at the molecular level, particularly in the context of translational control and metabolic regulation, offers insights that may lead to novel biomarkers or targets for intervention.

Compared to other gene editing methods, the LARP1B Gene Knockout Cell Lines are uniquely advantageous due to their specificity and reliability. Unlike traditional RNA interference techniques, which may lead to off-target effects and incomplete knockdown, the CRISPR/Cas9-generated knockout ensures a complete and permanent loss of function. This level of precision allows for more accurate data and reproducibility in experimental outcomes.

For researchers and clinicians looking to advance their studies in translational regulation and cancer biology, the LARP1B Gene Knockout Cell Lines represent a powerful resource. Our commitment to quality and innovation ensures that these cell lines are rigorously validated, providing researchers with confidence in their experimental design and results. With extensive experience in providing high-quality biological products, our company stands at the forefront of advancing scientific exploration and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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