Gene: LAMTOR4
Official Full Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 4provided by HGNC
Gene Summary: Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and protein localization to lysosome. Located in lysosome. Part of FNIP-folliculin RagC/D GAP and Ragulator complex. Is active in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09236 | LAMTOR4 Knockout cell line (HeLa) | Human | LAMTOR4 | 1:3~1:6 | Negative | Online Inquiry |
KO09237 | LAMTOR4 Knockout cell line (HCT 116) | Human | LAMTOR4 | 1:2~1:4 | Negative | Online Inquiry |
KO09238 | LAMTOR4 Knockout cell line (HEK293) | Human | LAMTOR4 | 1:3~1:6 | Negative | Online Inquiry |
LAMTOR4 Gene Knockout Cell Lines represent a cutting-edge biological research tool designed for the investigation of cellular processes and signaling pathways through the specific genetic disruption of the LAMTOR4 gene, which encodes a subunit of the late endosomal/multivesicular body (MVB) trafficking complex. This advanced cell line facilitates the study of LAMTOR4's role in endosomal trafficking, autophagy, and the immune response, providing researchers with invaluable insights into fundamental biological mechanisms.
The fundamental mechanism by which LAMTOR4 Gene Knockout Cell Lines operates involves targeted gene editing techniques, such as CRISPR/Cas9, to create precise deletions or disruptions in the LAMTOR4 gene. This leads to a lack of functional LAMTOR4 protein, enabling researchers to evaluate the downstream effects on signaling pathways, cellular growth, and differentiation. By comparing the knockout lines to wild-type or control cell lines, scientists can elucidate the specific contributions of LAMTOR4 in various cellular contexts.
The scientific importance of these cell lines is underscored by their applications across multiple research domains, including cancer biology, neurobiology, and immunology. By studying the functional consequences of LAMTOR4 loss, researchers can uncover new therapeutic targets and biomarkers for disease, thus facilitating the development of innovative treatment strategies.
What sets LAMTOR4 Gene Knockout Cell Lines apart from other genetically modified cell models is their precise gene knockout, allowing for true gene-function analysis rather than indirect assessment. As a product meticulously optimized for reproducibility and consistency, these cell lines are generated under stringent quality control measures, providing researchers with reliable data.
LAMTOR4 Gene Knockout Cell Lines are an essential asset for investigators seeking novel insights into LAMTOR4-related cellular functions, making them invaluable for both basic research and potential translational applications in clinical settings. Our company prides itself on its commitment to providing high-quality biological products backed by extensive scientific expertise, ensuring that researchers can rely on our tools to advance their work in gene-function studies. By choosing LAMTOR4 Gene Knockout Cell Lines, researchers gain access to a transformative resource that propels their investigations into the complexities of cellular behavior.
Please note that all services are for research use only. Not intended for any clinical use.
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