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LAMP1 Knockout Cell Lines

Gene: LAMP1

Official Full Name: lysosomal associated membrane protein 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00478 LAMP1 knockout cell line (HEK293) Human LAMP1 1:3~1:6 Negative Online Inquiry
KO02215 LAMP1 Knockout cell line (HeLa) Human LAMP1 1:3~1:6 Negative Online Inquiry
KO02216 LAMP1 Knockout cell line (HCT 116) Human LAMP1 1:2~1:4 Negative Online Inquiry
KO02217 LAMP1 Knockout cell line (A549) Human LAMP1 1:3~1:4 Negative Online Inquiry

Background

LAMP1 Gene Knockout Cell Lines represent a valuable set of cellular models specifically engineered to facilitate the study of lysosomal function and cellular homeostasis via the targeted disruption of the LAMP1 (Lysosomal Associated Membrane Protein 1) gene. This innovative product allows researchers to investigate the downstream effects of LAMP1 deficiency, which is critical for understanding a variety of cellular processes including autophagy, endocytosis, and lysosome biogenesis.

These cell lines operate by utilizing CRISPR-Cas9 technology to induce precise gene disruptions, effectively silencing LAMP1 expression. This knockout mechanism leads to notable lysosomal dysfunction, enabling researchers to observe alterations in cellular response pathways and the subsequent impact on cellular health. By employing LAMP1 Gene Knockout Cell Lines, scientists can gain insights into diseases associated with lysosomal storage disorders or neurodegenerative conditions, thus contributing to a greater understanding of human health and disease mechanisms.

The scientific importance of these cell lines extends beyond basic research; they hold significant potential for drug discovery and therapeutic development. The ability to model lysosomal deficiencies can pave the way for new interventions targeting conditions such as Alzheimer's disease, Pompe disease, and other disorders linked to lysosomal dysfunction.

One of the unique selling points of LAMP1 Gene Knockout Cell Lines is their reproducibility and reliability when compared to alternative models that may involve transient knockdown methods. This stable knockout allows for consistent results over time, making it a superior choice for long-term studies. In addition, these cell lines come with detailed characterization data, aiding in the validation of experimental findings.

For researchers, clinicians, and pharmaceutical developers focused on advancing the understanding of lysosomal functions and associated diseases, LAMP1 Gene Knockout Cell Lines offer unparalleled specificity and adaptability. They serve as an essential tool for driving scientific discovery and innovation.

Our company's expertise in cell line development, coupled with a commitment to advancing research in cellular biology, ensures that we provide high-quality, rigorously validated products. With a focus on delivering effective solutions for your research needs, we stand ready to support your work with LAMP1 Gene Knockout Cell Lines and other premier biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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