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L3MBTL2 Knockout Cell Lines

Gene: L3MBTL2

Official Full Name: L3MBTL histone methyl-lysine binding protein 2provided by HGNC

Gene Summary: Enables methylated histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including ectoderm development; stem cell differentiation; and stem cell proliferation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05216 L3MBTL2 Knockout cell line (HeLa) Human L3MBTL2 1:3~1:6 Negative Online Inquiry
KO05217 L3MBTL2 Knockout cell line (HCT 116) Human L3MBTL2 1:2~1:4 Negative Online Inquiry
KO05218 L3MBTL2 Knockout cell line (HEK293) Human L3MBTL2 1:3~1:6 Negative Online Inquiry
KO05219 L3MBTL2 Knockout cell line (A549) Human L3MBTL2 1:3~1:4 Negative Online Inquiry

Background

L3MBTL2 Gene Knockout Cell Lines represent a critical innovation in molecular biology research, specifically designed to analyze the functional roles of the L3MBTL2 gene. These cell lines have undergone targeted gene editing, utilizing CRISPR-Cas9 technology to create knockout variants that lack the expression of L3MBTL2. This precise manipulation enables researchers to investigate the gene's involvement in various biological pathways and disease processes, including cancer and neurodevelopmental disorders.

The primary function of L3MBTL2 is its role as a multifunctional epigenetic regulator involved in chromatin remodeling and transcriptional regulation. By employing these knockout cell lines, researchers can elucidate the mechanisms by which L3MBTL2 influences gene expression, cell proliferation, and differentiation. This understanding is pivotal for advancing therapeutic strategies aimed at diseases associated with aberrant gene regulation.

In terms of scientific importance, these cell lines provide a robust platform for high-throughput screening of small molecules and gene interactions, allowing for the exploration of potential pharmacological targets. Their applications extend to functional genomics studies, cancer research, and investigations into stem cell biology. The ability to perform pathway analyses in a controlled environment enhances the replicability and accuracy of experimental outcomes.

Compared to traditional cell lines, the L3MBTL2 Gene Knockout Cell Lines present unique advantages such as a defined genetic background, improved specificity in studying the role of the L3MBTL2 gene, and the potential for downstream applications in therapeutic development. Researchers will find these knockout lines to be indispensable tools in their quest to unravel complex molecular mechanisms with potential clinical implications.

Our company has a proven track record in developing high-performance biological products tailored for cutting-edge research in genetics and epigenetics. With a commitment to quality and innovation, we provide researchers and clinicians with reliable tools to facilitate groundbreaking discoveries in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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