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KRT222 Knockout Cell Lines

Gene: KRT222

Official Full Name: keratin 222provided by HGNC

Gene Summary: Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27692 KRT222 Knockout cell line (HCT 116) Human KRT222 1:2~1:4 Negative Online Inquiry
KO27693 KRT222 Knockout cell line (HEK293) Human KRT222 1:3~1:6 Negative Online Inquiry
KO27694 KRT222 Knockout cell line (A549) Human KRT222 1:3~1:4 Negative Online Inquiry

Background

KRT222 Gene Knockout Cell Lines are advanced biological models specifically engineered to facilitate the study of gene function and the effects of gene silencing in various cellular contexts. This innovative product is derived from established cell lines that have been meticulously edited using CRISPR-Cas9 technology to produce targeted gene knockout of the KRT222 locus. The resulting cell lines allow for detailed investigation into the biological pathways influenced by this gene, providing insights relevant across multiple fields of research, including developmental biology, cancer research, and regenerative medicine.

The primary mechanism behind the KRT222 Gene Knockout Cell Lines involves the precise deletion of the KRT222 gene, leading to the absence of its encoded protein. This alteration enables researchers to observe phenotypic changes, alterations in cellular signaling, and downstream effects on gene expression. Such capabilities are pivotal in elucidating the gene's role in essential cellular processes, such as proliferation, differentiation, and response to stress.

The scientific importance of these knockout cell lines cannot be overstated. They serve as vital tools in both academic and industrial research settings, supporting experiments aimed at understanding genetic diseases, drug development, and the discovery of novel therapeutic targets. The KRT222 Gene Knockout Cell Lines also allow for high-throughput screening approaches that can accelerate the identification of candidate compounds for further testing.

Compared to traditional methods, such as RNA interference or chemical inhibitors, KRT222 Gene Knockout Cell Lines offer a more definitive and long-lasting approach to gene silencing. The CRISPR methodology provides a clear, permanent alteration of the genome, leading to more consistent and reliable results, which is crucial for reproducibility in scientific research.

For researchers, clinicians, and biotech developers, the KRT222 Gene Knockout Cell Lines represent a significant advancement in the toolkit available for genetic studies, contributing to a deeper understanding of molecular mechanisms driving health and disease. Our company, renowned for its commitment to excellence in the development of validated biological products, provides KRT222 Gene Knockout Cell Lines as part of a diverse portfolio aimed at supporting groundbreaking research and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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