Gene: KPTN
Official Full Name: kaptin, actin binding proteinprovided by HGNC
Gene Summary: This gene encodes a filamentous-actin-associated protein, which is involved in actin dynamics and plays an important role in neuromorphogenesis. This protein is part of the KICSTOR protein complex that localizes to lysosomes. Mutations in this gene result in an autosomal recessive form of intellectual disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31169 | KPTN Knockout cell line (HeLa) | Human | KPTN | 1:3~1:6 | Negative | Online Inquiry |
KO31170 | KPTN Knockout cell line (HCT 116) | Human | KPTN | 1:2~1:4 | Negative | Online Inquiry |
KO31171 | KPTN Knockout cell line (HEK293) | Human | KPTN | 1:3~1:6 | Negative | Online Inquiry |
KO31172 | KPTN Knockout cell line (A549) | Human | KPTN | 1:3~1:4 | Negative | Online Inquiry |
KPTN Gene Knockout Cell Lines are genetically modified cell lines designed specifically for the study of KPTN (Kinectin 1) gene function in various biological contexts. These cell lines have undergone precise genomic editing to eliminate KPTN expression, facilitating investigations into its role in cellular processes such as cytoskeletal dynamics, cell motility, and signal transduction.
The primary mechanisms governing the functionality of these knockout cell lines lie in their utility as model systems. By providing a controlled environment where the KPTN gene is inactivated, researchers can observe resultant phenotypic changes, elucidate signaling pathways, and contribute to the understanding of KPTN-related pathophysiological conditions. Moreover, KPTN Gene Knockout Cell Lines enable comparative studies with wild-type counterparts, offering insights into gene function and regulation.
From a scientific perspective, these knockout cell lines hold significant promise in both research and clinical applications. They may be utilized to explore potential therapeutic targets in diseases where KPTN has been implicated, such as certain cancers and neurodevelopmental disorders. The ability to study gene function in a versatile, human-derived cellular model is invaluable, particularly for drug discovery and development.
Unlike alternative products on the market, KPTN Gene Knockout Cell Lines are distinguished by their high efficiency of gene editing, robust characterization, and ease of use within a variety of laboratory protocols. Additionally, our proprietary technology ensures that these cell lines maintain stability across passages, minimizing variability in experimental results.
For researchers and clinicians, the value of KPTN Gene Knockout Cell Lines lies not only in their advanced design but also in their potential to accelerate biomedical research and translational medicine. As experts in genetic modification and cell line development, our company is committed to providing high-quality biological tools that empower scientific inquiry and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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