Gene: KLF9
Official Full Name: KLF transcription factor 9provided by HGNC
Gene Summary: The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02560 | KLF9 Knockout cell line (HeLa) | Human | KLF9 | 1:3~1:6 | Negative | Online Inquiry |
KO02561 | KLF9 Knockout cell line (HCT 116) | Human | KLF9 | 1:2~1:4 | Negative | Online Inquiry |
KO02562 | KLF9 Knockout cell line (HEK293) | Human | KLF9 | 1:3~1:6 | Negative | Online Inquiry |
KO02563 | KLF9 Knockout cell line (A549) | Human | KLF9 | 1:3~1:4 | Negative | Online Inquiry |
KLF9 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the Krüppel-like factor 9 (KLF9) gene's functions and regulatory pathways. KLF9 is a transcription factor implicated in various biological processes, including cell differentiation, proliferation, and response to stress. The knockout of this gene enables researchers to observe phenotypic alterations and gain insights into its roles in cellular mechanisms, inflammation, and disorders such as cancer and metabolic diseases.
These cell lines operate through the CRISPR-Cas9 gene-editing technology, which provides a precise and efficient means of creating targeted gene disruptions. By specifically knocking out the KLF9 gene, scientists can utilize these cell lines to elucidate the gene’s contributions to various biological responses, thereby unraveling complex molecular networks. Consequently, these models serve as invaluable tools in both basic and applied research, enabling the exploration of gene-function relationships and the development of potential therapeutic interventions.
The scientific importance of KLF9 Gene Knockout Cell Lines lies in their broad applications across diverse research areas, including pharmacology, developmental biology, and toxicology. These models can be pivotal in drug discovery and validation by allowing researchers to identify novel compounds that may modulate KLF9-related pathways. Furthermore, they can provide greater understanding for clinicians seeking to devise targeted therapies linked to KLF9 dysregulation.
Compared to alternative models, such as wild-type or overexpression systems, KLF9 knockout cell lines provide a direct approach to studying loss-of-function scenarios, offering clearer insights into gene activity and its absence. The specificity and reproducibility of these engineered lines enhance the reliability of experimental outcomes, which are crucial for advancing scientific knowledge and therapeutic applications.
For researchers and clinicians focused on innovative approaches to understanding gene function and its implications in disease, KLF9 Gene Knockout Cell Lines present an indispensable resource. They not only streamline experimentation but also accelerate the translation of findings from bench to bedside. Our company prides itself on delivering high-quality genetic tools, backed by a team of experts dedicated to advancing biological research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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