Gene: KIFC2
Official Full Name: kinesin family member C2provided by HGNC
Gene Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement and mitotic spindle assembly. Predicted to be located in cytoskeleton. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23592 | KIFC2 Knockout cell line (HeLa) | Human | KIFC2 | 1:3~1:6 | Negative | Online Inquiry |
KO23593 | KIFC2 Knockout cell line (HCT 116) | Human | KIFC2 | 1:2~1:4 | Negative | Online Inquiry |
KO23594 | KIFC2 Knockout cell line (HEK293) | Human | KIFC2 | 1:3~1:6 | Negative | Online Inquiry |
KO23595 | KIFC2 Knockout cell line (A549) | Human | KIFC2 | 1:3~1:4 | Negative | Online Inquiry |
KIFC2 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the functions and regulatory mechanisms of the KIFC2 gene, which encodes a kinesin motor protein critical for cellular processes such as mitosis and intracellular transport. These cell lines have been meticulously created using advanced CRISPR-Cas9 gene-editing technologies, resulting in targeted disruptions of the KIFC2 gene. This knockout approach allows researchers to investigate the consequences of KIFC2 loss-of-function, providing insights into the role of this gene in cellular dynamics and potential implications in cancer and neurodegenerative diseases.
The key function of KIFC2 lies in its involvement in the organization of the mitotic spindle during cell division. By using these knockout cell lines, scientists can elucidate the molecular pathways by which KIFC2 influences microtubule dynamics and cell cycle regulation. The ability to observe phenotypic changes, such as alterations in cell proliferation, morphology, and response to chemotherapeutic agents, can provide valuable information about KIFC2’s contributions to cellular health and disease.
The scientific importance of KIFC2 Gene Knockout Cell Lines extends to various applications, including cancer research, studies on genetic disorders, and drug development. By establishing a precise model of gene knockout, researchers can conduct functional assays that correlate KIFC2 activity with disease mechanisms in vitro, thus paving the way for new therapeutic strategies.
What sets these KIFC2 Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability, which stem from the precision CRISPR-Cas9 methodology employed in their development. Other knockout systems may yield off-target effects or unexpected compensation from other genes, but our cell lines promise robust reproducibility, ensuring that findings are both accurate and translatable to broader biological contexts.
For researchers and clinicians, these cell lines represent a powerful tool in dissecting the intricate roles of KIFC2, aiding in the pursuit of targeted therapies and personalized medicine approaches. The ability to manipulate and study the KIFC2 gene in a controlled manner underscores the value of this biological product in advancing scientific knowledge and therapeutic innovation.
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