Gene: KIFC1
Official Full Name: kinesin family member C1provided by HGNC
Gene Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and minus-end-directed microtubule motor activity. Involved in mitotic metaphase chromosome alignment and mitotic spindle assembly. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04007 | KIFC1 Knockout cell line (HeLa) | Human | KIFC1 | 1:3~1:6 | Negative | Online Inquiry |
KO04008 | KIFC1 Knockout cell line (HCT 116) | Human | KIFC1 | 1:2~1:4 | Negative | Online Inquiry |
KO04009 | KIFC1 Knockout cell line (HEK293) | Human | KIFC1 | 1:3~1:6 | Negative | Online Inquiry |
KO04010 | KIFC1 Knockout cell line (A549) | Human | KIFC1 | 1:3~1:4 | Negative | Online Inquiry |
KIFC1 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the KIFC1 gene, which encodes a motor protein involved in mitosis and intracellular transport. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines have been manufactured to exhibit a complete knockout of the KIFC1 gene, providing researchers with a powerful tool to investigate the gene's role in various biological processes and disease states.
The primary function of KIFC1 is to participate in the transport of cellular components along microtubules, particularly during cell division. The disruption of this gene allows for the examination of its contributions to cellular dynamics and the potential implications of its dysfunction in diseases such as cancer. Through the use of these knockout cell lines, researchers can elucidate the signaling pathways and biological mechanisms that are modulated by KIFC1, thereby enhancing the understanding of its involvement in mitotic progression and other cellular functions.
The scientific significance of KIFC1 Gene Knockout Cell Lines lies in their applicability in both fundamental and applied research settings. They can be utilized in drug screening assays, studies of cell cycle progression, and investigations into the mechanisms of oncogenesis. Additionally, these cell lines can serve as valuable models in the development of personalized medicine strategies, enabling the identification of targeted therapeutic approaches for conditions linked to cell cycle dysregulation.
Compared to alternative models, such as RNA interference systems or non-genetically modified cell lines, KIFC1 Gene Knockout Cell Lines offer a more stable and definitive method for studying gene function. Researchers benefit from the complete gene loss, eliminating off-target effects and allowing for clearer interpretations of experimental outcomes. This specificity makes these cell lines highly advantageous for focused studies on the KIFC1 gene and its mechanistic pathways.
For researchers and clinicians seeking to advance their understanding of cell biology and pathology, KIFC1 Gene Knockout Cell Lines represent a significant asset. They not only enhance the capacity for rigorous scientific inquiry but also provide insights that can pave the way for innovative therapeutic solutions. Our company, with its commitment to the advancement of biomedical knowledge, takes pride in delivering high-quality genetic models that empower cutting-edge research and discovery in diverse fields.
Please note that all services are for research use only. Not intended for any clinical use.
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