Gene: KIF3A
Official Full Name: kinesin family member 3Aprovided by HGNC
Gene Summary: Enables protein phosphatase binding activity; small GTPase binding activity; and spectrin binding activity. Involved in protein localization to cell junction and protein transport. Located in centriole; centrosome; and spindle microtubule. Part of kinesin II complex. Biomarker of silicosis. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10042 | KIF3A Knockout cell line (HeLa) | Human | KIF3A | 1:3~1:6 | Negative | Online Inquiry |
KO10043 | KIF3A Knockout cell line (HCT 116) | Human | KIF3A | 1:2~1:4 | Negative | Online Inquiry |
KO10044 | KIF3A Knockout cell line (HEK293) | Human | KIF3A | 1:3~1:6 | Negative | Online Inquiry |
KO10045 | KIF3A Knockout cell line (A549) | Human | KIF3A | 1:3~1:4 | Negative | Online Inquiry |
KIF3A Gene Knockout Cell Lines are sophisticated biological tools designed to study the function and role of the KIF3A gene in various cellular processes. KIF3A, a member of the Kinesin family of motor proteins, is critical for intracellular transport, influencing cellular dynamics, mitosis, and organelle distribution. The knockout of this gene allows researchers to delve into its physiological roles and implications in diseases, facilitating the exploration of KIF3A’s contributions to cellular transport mechanisms and developmental biology.
These cell lines are engineered to lack the KIF3A gene, providing a unique in vitro model to investigate the cellular pathways and mechanisms impacted by this gene alteration. By utilizing techniques such as CRISPR/Cas9 for precise gene editing, these knockout cell lines enable researchers to observe the resulting phenotypic changes, including alterations in cell morphology, movement, and proliferation, establishing a direct correlation between KIF3A expression and cellular function.
The scientific significance of KIF3A Gene Knockout Cell Lines extends beyond basic research; they hold substantial promise in clinical settings, especially in understanding neurodegenerative disorders and other diseases linked to dysfunctional transport mechanisms. Their high fidelity and specificity make them an invaluable asset for drug discovery and validation of therapeutic targets related to KIF3A.
Compared to other knockout models, KIF3A Gene Knockout Cell Lines offer advantages such as established genetic backgrounds, reproducibility in experiments, and comprehensive support for downstream analyses. These characteristics enhance the reliability of experimental results and contribute to a more profound understanding of KIF3A's role in health and disease.
For researchers and clinicians seeking to uncover new therapeutic opportunities or to verify hypotheses at the molecular level, KIF3A Gene Knockout Cell Lines represent an essential tool. Our company prides itself on providing high-quality biological products, backed by expert knowledge and advanced technology, ensuring that you have the resources needed to propel your research forward effectively and efficiently.
Please note that all services are for research use only. Not intended for any clinical use.
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