Gene: KCTD18
Official Full Name: potassium channel tetramerization domain containing 18provided by HGNC
Gene Summary: Predicted to enable identical protein binding activity. Predicted to be involved in monoatomic ion transmembrane transport and protein homooligomerization. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26618 | KCTD18 Knockout cell line (HeLa) | Human | KCTD18 | 1:3~1:6 | Negative | Online Inquiry |
KO26619 | KCTD18 Knockout cell line (HCT 116) | Human | KCTD18 | 1:2~1:4 | Negative | Online Inquiry |
KO26620 | KCTD18 Knockout cell line (HEK293) | Human | KCTD18 | 1:3~1:6 | Negative | Online Inquiry |
KO26621 | KCTD18 Knockout cell line (A549) | Human | KCTD18 | 1:3~1:4 | Negative | Online Inquiry |
KCTD18 Gene Knockout Cell Lines are specialized cellular models that have undergone precise genetic modifications to abrogate the expression of the KCTD18 gene. KCTD18, or Potassium Channel Tetramerization Domain Containing 18, is implicated in various cellular processes, including potassium ion channel regulation and potentially influencing cellular signal transduction pathways. By creating knockout cell lines, researchers can investigate the gene's loss-of-function effects, providing insights into its role in physiological and pathological contexts.
Functionally, these knockout cell lines permit the study of KCTD18's involvement in ion channel activity, cellular proliferation, and differentiation. The mechanism of action primarily revolves around the disruption of the gene's coding sequence, leading to a lack of corresponding protein product. This loss allows scientists to explore the downstream effects on cell behavior and signaling pathways, thereby elucidating the gene’s role in health and disease.
The scientific significance of KCTD18 Gene Knockout Cell Lines extends to diverse applications, including drug discovery, understanding genetic contributions to diseases, and exploring fundamental biological processes. In clinical settings, these models can serve as powerful tools for testing therapeutic interventions aimed at diseases linked to potassium channel dysfunction, such as certain cardiac and neurological disorders.
Compared to alternative models, KCTD18 Gene Knockout Cell Lines offer a high degree of specificity and reliability. These knockout lines provide definitive evidence of gene function without the confounding effects of residual protein expression that can occur in knockdown approaches. Their user-friendly nature ensures rapid integration into existing research pipelines, making them an attractive choice for researchers aiming for high throughput and reproducibility in experimental settings.
Investing in KCTD18 Gene Knockout Cell Lines equips researchers and clinicians with a superior tool for unraveling complex biological mechanisms, advancing therapeutic strategies, and accelerating drug development processes. With a commitment to scientific excellence, our company brings years of expertise in producing high-quality cellular models tailored to meet rigorous research needs, ensuring that researchers have the confidence to push the boundaries of discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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