Gene: KCTD13
Official Full Name: potassium channel tetramerization domain containing 13provided by HGNC
Gene Summary: Enables identical protein binding activity and small GTPase binding activity. Contributes to ubiquitin-protein transferase activity. Involved in several processes, including negative regulation of Rho protein signal transduction; proteasome-mediated ubiquitin-dependent protein catabolic process; and stress fiber assembly. Located in nuclear body. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21194 | KCTD13 Knockout cell line (HeLa) | Human | KCTD13 | 1:3~1:6 | Negative | Online Inquiry |
KO21195 | KCTD13 Knockout cell line (HCT 116) | Human | KCTD13 | 1:2~1:4 | Negative | Online Inquiry |
KO21196 | KCTD13 Knockout cell line (HEK293) | Human | KCTD13 | 1:3~1:6 | Negative | Online Inquiry |
KO21197 | KCTD13 Knockout cell line (A549) | Human | KCTD13 | 1:3~1:4 | Negative | Online Inquiry |
KCTD13 Gene Knockout Cell Lines are specialized cellular models in which the KCTD13 gene has been systematically disrupted using CRISPR-Cas9 technology. KCTD13 (Potassium Channel Tetramerization Domain Containing 13) is implicated in various cellular processes, including cell proliferation and neuronal function. By knocking out this gene, researchers obtain valuable insights into its role in cellular pathways, making these cell lines crucial for investigating the functional consequences of KCTD13 absence.
The mechanism by which KCTD13 gene knockout operates involves targeted editing of the genomic DNA, allowing for precise removal of the gene in question. The cells are then validated through genotyping and functional assays to confirm the successful disruption of KCTD13. This leads to a model system where the downstream effects can be studied, helping elucidate KCTD13's involvement in diseases such as autism spectrum disorders and other neurodevelopmental conditions.
The scientific importance of KCTD13 knockout cell lines underscores their applications in both research and clinical settings. They serve as foundational tools for drug development, pathway analysis, and for understanding the molecular bases of disorders linked to KCTD13 dysfunction. Researchers can leverage these models to explore potential therapeutic targets and molecular interactions, significantly advancing the field of genetic research.
What sets KCTD13 Gene Knockout Cell Lines apart from alternatives is their high fidelity and versatility. Unlike transient knockdown methods, these stable knockout cell lines provide long-term studies, ensuring reproducible results in various experiments. Additionally, they offer biologically relevant insights, reducing the gap between cell culture and in vivo models.
This product is a valuable asset for researchers and clinicians who aim to innovate in the fields of genetics, neurobiology, and pharmacology. By utilizing KCTD13 knockout cell lines, users gain access to a powerful tool for dissecting gene function and exploring novel therapeutic avenues, thereby accelerating scientific discovery.
Our company is a leader in the development of cutting-edge biological products, offering a comprehensive range of genetically modified cell lines designed for advanced research. With a commitment to quality and innovation, we provide researchers with the tools they need to push the boundaries of science.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.