Gene: KCTD12
Official Full Name: potassium channel tetramerization domain containing 12provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Predicted to be located in cell projection; plasma membrane; and synapse. Predicted to be part of receptor complex. Predicted to be active in GABA-ergic synapse; postsynaptic membrane; and presynaptic active zone membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30636 | KCTD12 Knockout cell line (HeLa) | Human | KCTD12 | 1:3~1:6 | Negative | Online Inquiry |
KO30637 | KCTD12 Knockout cell line (HCT 116) | Human | KCTD12 | 1:2~1:4 | Negative | Online Inquiry |
KO30638 | KCTD12 Knockout cell line (HEK293) | Human | KCTD12 | 1:3~1:6 | Negative | Online Inquiry |
KCTD12 Gene Knockout Cell Lines are engineered cellular models that have had the KCTD12 gene disrupted, enabling researchers to study the functional implications of this gene in various biological contexts. KCTD12, known for its role in modulating signaling pathways and influencing cellular processes such as proliferation and differentiation, presents a unique opportunity for investigating its contributions to disease states and cellular behaviors.
The key function of KCTD12 Gene Knockout Cell Lines lies in their ability to mimic gene deficiency conditions, allowing thorough exploration of the underlying mechanisms in gene function and regulation. By utilizing CRISPR/Cas9 or similar gene-editing technologies, these knockout cells facilitate a precise elimination of the KCTD12 gene, thereby providing a model to assess changes in cellular signaling, protein interactions, and gene expression levels. This functional knockout can lead to the identification of new therapeutic targets, thereby propelling advancements in personalized medicine and targeted therapies.
Scientifically, KCTD12 has been implicated in various conditions, including neurodevelopmental disorders and cancers, making these cell lines of great importance for both research and clinical settings. They can be utilized in drug discovery, toxicology assessments, and basic biology studies. The high specificity of targeting the KCTD12 gene enables distinct differentiation of its effects from related genes or pathways, thus offering clarity essential for robust experimental conclusions.
What sets KCTD12 Gene Knockout Cell Lines apart from alternatives is their carefully validated mechanism of gene disruption, coupled with reliable performance metrics in terms of consistency and reproducibility. This reliability is fundamental for generating data that researchers can trust to drive forward their hypotheses and experiments. Furthermore, our commitment to continual improvements and user support ensures that our clients can maximize their research potential.
The availability of KCTD12 Gene Knockout Cell Lines highlights our dedication to advancing biological science through cutting-edge technology and meticulously designed products. Our extensive experience in genetic engineering and cell line development translates into high-quality offerings that empower scientists to unravel the complexities of gene function.
Please note that all services are for research use only. Not intended for any clinical use.
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