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KCNK1 Knockout Cell Lines

Gene: KCNK1

Official Full Name: potassium two pore domain channel subfamily K member 1provided by HGNC

Gene Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36974 KCNK1 Knockout cell line (HeLa) Human KCNK1 1:3~1:6 Negative Online Inquiry
KO36975 KCNK1 Knockout cell line (HCT 116) Human KCNK1 1:2~1:4 Negative Online Inquiry
KO36976 KCNK1 Knockout cell line (HEK293) Human KCNK1 1:3~1:6 Negative Online Inquiry
KO36977 KCNK1 Knockout cell line (A549) Human KCNK1 1:3~1:4 Negative Online Inquiry

Background

KCNK1 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically disrupt the KCNK1 gene, responsible for encoding a potassium channel that plays a crucial role in maintaining cellular excitability and ion homeostasis. This manipulation allows researchers to delve into the physiological and pathological roles of the KCNK1 protein, elucidating its function in various cellular processes, including neuronal signaling, muscle contraction, and cardiovascular function. The knockout strategy involves sophisticated gene editing techniques that ensure specificity and efficiency in disrupting the target gene, resulting in a cellular phenotype that provides insightful data on KCNK1's biological functions.

These cell lines serve as invaluable tools in both research and clinical applications, enabling the investigation of the ion channel’s involvement in health and disease, including neurological disorders and cardiac arrhythmias. By understanding the mechanisms through which KCNK1 influences cellular behavior, researchers can identify potential therapeutic targets and develop new treatment strategies.

One significant advantage of KCNK1 Gene Knockout Cell Lines is their capability to model human disease accurately, as these lines maintain the relevant biological pathways in a controlled environment. Unlike alternative models, such as animal models or primary cells, these knockout cell lines provide a reproducible and scalable approach for experimental manipulation and high-throughput screening, leading to efficient drug discovery and validation processes.

For researchers and clinicians, the value of KCNK1 Gene Knockout Cell Lines lies in their capacity to contribute to cutting-edge studies into ion channel biology, fostering innovations in the treatment of related diseases. They represent a crucial asset for academic laboratories and biotechnology companies seeking to advance the frontiers of scientific knowledge and therapeutic development.

Our company prides itself on its expertise in providing high-quality, well-characterized gene knockout cell lines, dedicated to supporting the scientific community's quest for breakthrough discoveries and advancements in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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