Gene: KBTBD7
Official Full Name: kelch repeat and BTB domain containing 7provided by HGNC
Gene Summary: The protein encoded by this gene is a transcriptional activator, having been shown to increase the transcription of activator protein-1 and serum response element. The encoded protein can also form a complex with KBTBD6 and CUL3, which regulates the ubiquitylation and degradation of TIAM1, which is a regulator of RAC1. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25216 | KBTBD7 Knockout cell line (HeLa) | Human | KBTBD7 | 1:3~1:6 | Negative | Online Inquiry |
KO25217 | KBTBD7 Knockout cell line (HCT 116) | Human | KBTBD7 | 1:2~1:4 | Negative | Online Inquiry |
KO25218 | KBTBD7 Knockout cell line (HEK293) | Human | KBTBD7 | 1:3~1:6 | Negative | Online Inquiry |
KO25219 | KBTBD7 Knockout cell line (A549) | Human | KBTBD7 | 1:3~1:4 | Negative | Online Inquiry |
KBTBD7 Gene Knockout Cell Lines are a specialized tool developed for in-depth functional genomics studies. These cell lines are genetically engineered to specifically interrupt the expression of the KBTBD7 gene, which encodes a protein implicated in various cellular processes, including cell cycle regulation and response to stress. By creating a knockout model, researchers can observe the phenotypic changes resulting from the absence of this gene, thereby illuminating its role in biological pathways and disease mechanisms.
The primary mechanism of action for KBTBD7 Gene Knockout Cell Lines involves the targeted disruption of the KBTBD7 gene through CRISPR-Cas9 technology or similar genome-editing systems. This precise approach leads to the creation of a loss-of-function model, which is vital for studying gene function and elucidating its contributions to cellular behaviors and responses. This tool is particularly crucial in research settings focusing on cancer biology, neurodevelopmental disorders, and any condition where KBTBD7 is implicated.
From a scientific standpoint, these knockout cell lines are invaluable for establishing the causal relationships between gene expression and cellular phenotype, enabling researchers to perform high-throughput screenings, validate drug targets, and explore gene interactions within signaling pathways. Compared to traditional methods, such as RNA interference, KBTBD7 knockout cell lines offer a more stable and reliable means of gene disruption, leading to reproducible results crucial for experimental integrity.
The unique selling points of our KBTBD7 Gene Knockout Cell Lines lie in their specificity, robustness, and ease of use, all of which facilitate streamlined workflows in both laboratory and translational research settings. Researchers and clinicians alike will find these cell lines particularly advantageous for exploring therapeutic avenues and understanding disease mechanisms, as they provide a clear and controlled method to investigate gene function.
Our company prides itself on a commitment to advancing scientific research through high-quality biological products. With expertise in genetic engineering and an unwavering focus on innovation, we deliver solutions that empower scientists and clinicians to make breakthroughs in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.