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KBTBD4 Knockout Cell Lines

Gene: KBTBD4

Official Full Name: kelch repeat and BTB domain containing 4provided by HGNC

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16834 KBTBD4 Knockout cell line (HeLa) Human KBTBD4 1:3~1:6 Negative Online Inquiry
KO16835 KBTBD4 Knockout cell line (HCT 116) Human KBTBD4 1:2~1:4 Negative Online Inquiry
KO16836 KBTBD4 Knockout cell line (HEK293) Human KBTBD4 1:3~1:6 Negative Online Inquiry
KO16837 KBTBD4 Knockout cell line (A549) Human KBTBD4 1:3~1:4 Negative Online Inquiry

Background

KBTBD4 Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate the study of the KBTBD4 gene, which encodes a member of the Kelch-like protein family associated with various cellular processes, including protein degradation pathways and signal transduction mechanisms. These knockout cell lines have been meticulously developed to eliminate the expression of the KBTBD4 gene, enabling researchers to investigate its functional role and contributions to cellular phenotypes under both physiological and pathological conditions.

The primary function of KBTBD4 involves its interaction with the ubiquitin-proteasome system, where it plays a role in the regulation of protein homeostasis. By utilizing these knockout cell lines, scientists can analyze how the absence of KBTBD4 affects crucial processes such as cell cycle regulation, apoptosis, and response to stressors, leading to insights into its implications in diseases, particularly cancer and neurodegenerative disorders.

The scientific importance of KBTBD4 Gene Knockout Cell Lines lies in their potential applications across multiple research domains, including cancer biology, neurobiology, and cellular signaling pathways. By understanding the gene's function, researchers can design targeted therapies or validate new drug compounds, thereby advancing both basic and translational scientific agendas.

Compared to traditional research methods, such as siRNA-mediated knockdown, the use of knockout cell lines offers a more stable and definitive approach to gene silencing, thus allowing for more reproducible results. This permanence facilitates long-term studies, enabling a deeper exploration of compensatory mechanisms and the effects of prolonged gene loss on cellular behavior.

For researchers and clinicians focused on elucidating the complexities of gene function, KBTBD4 Gene Knockout Cell Lines provide an invaluable tool for advancing the understanding of gene-related pathologies and exploring innovative therapeutic strategies. Our company prides itself on its commitment to high-quality, rigorously validated biological products tailored for research excellence. By choosing our knockout cell lines, users gain access to advanced scientific tools that are instrumental in driving forward their research outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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