Gene: JTB
Official Full Name: jumping translocation breakpointprovided by HGNC
Gene Summary: Enables protein kinase binding activity. Involved in mitotic cytokinesis and positive regulation of protein kinase activity. Located in cytoplasm; microtubule cytoskeleton; and midbody. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31437 | JTB Knockout cell line (HeLa) | Human | JTB | 1:3~1:6 | Negative | Online Inquiry |
KO31438 | JTB Knockout cell line (HCT 116) | Human | JTB | 1:2~1:4 | Negative | Online Inquiry |
KO31439 | JTB Knockout cell line (HEK293) | Human | JTB | 1:3~1:6 | Negative | Online Inquiry |
KO31440 | JTB Knockout cell line (A549) | Human | JTB | 1:3~1:4 | Negative | Online Inquiry |
JTB Gene Knockout Cell Lines are engineered cell lines that have undergone precise gene editing to remove or "knock out" specific target genes. Utilizing advanced technologies such as CRISPR-Cas9, these cell lines are meticulously designed to elucidate the role of particular genes in various biological processes and disease models. By targeting genes relevant to cellular functions, researchers can study the resulting phenotypic changes, thereby gaining insights into gene function and the underlying mechanisms of diseases.
The primary mechanisms through which JTB Gene Knockout Cell Lines operate involve gene disruption that leads to the loss of protein expression. This allows for the direct assessment of gene function in pathways related to disease, cellular metabolism, and responses to therapeutic agents. Researchers may utilize these knockout models to explore the effects of gene ablation on cell signaling, proliferation, differentiation, and apoptosis, among other vital cellular processes.
In scientific research and clinical settings, the importance of JTB Gene Knockout Cell Lines cannot be overstated. They serve as a crucial tool for biomedical research, providing invaluable insights that drive the discovery of novel therapeutics and the development of targeted treatment strategies. The use of these models accelerates drug discovery by enabling the identification of potential drug targets and verifying the efficacy of new compounds in a controlled environment.
Compared to traditional cell lines and other genetic modification techniques, JTB Gene Knockout Cell Lines boast a high degree of specificity and reproducibility. They offer a faster turnaround for experimental results due to their well-characterized nature and the availability of multiple knockout variants for the same gene, allowing for comprehensive assessments. Furthermore, their compatibility with various culture conditions and experimental techniques makes them versatile tools for a range of applications.
For researchers and clinicians, the value of JTB Gene Knockout Cell Lines extends beyond basic research; they represent a critical asset for understanding complex diseases, validating gene function in translational research, and advancing precision medicine. When selecting models for gene function studies or pharmaceutical testing, the reliability and accuracy of JTB Gene Knockout Cell Lines provide a distinct advantage.
With a commitment to cutting-edge science and innovation, our company specializes in the development and production of high-quality biological products, including these knockout cell lines. Our expertise ensures that researchers have access to reliable and effective tools essential for advancing their scientific inquiries and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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