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JMJD6 Knockout Cell Lines

Gene: JMJD6

Official Full Name: jumonji domain containing 6, arginine demethylase and lysine hydroxylaseprovided by HGNC

Gene Summary: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03027 JMJD6 Knockout cell line (HeLa) Human JMJD6 1:3~1:6 Negative Online Inquiry
KO03028 JMJD6 Knockout cell line (HCT 116) Human JMJD6 1:2~1:4 Negative Online Inquiry
KO03029 JMJD6 Knockout cell line (HEK293) Human JMJD6 1:3~1:6 Negative Online Inquiry
KO03030 JMJD6 Knockout cell line (A549) Human JMJD6 1:3~1:4 Negative Online Inquiry

Background

JMJD6 Gene Knockout Cell Lines are an innovative biological product designed to facilitate the study of the JMJD6 gene's role in various biological processes. JMJD6, a member of the Jumonji domain-containing protein family, is implicated in the regulation of gene expression through histone demethylation and is crucial for developmental processes and cellular differentiation. Our knockout cell lines specifically lack functional expression of the JMJD6 gene, allowing researchers to investigate its functions, interactions, and regulatory mechanisms in a controlled environment.

The key functions of JMJD6 involve the modulation of histone and non-histone proteins, thereby influencing chromatin remodeling and epigenetic regulation. By utilizing our JMJD6 knockout cell lines, researchers can elucidate the effects of JMJD6 absence on cellular metabolism, signaling pathways, and overall cellular behavior. This product provides a robust platform for studying the gene’s implications in diseases such as cancer, neurodegeneration, and metabolic disorders.

The scientific importance of JMJD6 knockout cell lines extends to both basic and applied research. They are invaluable for gene function studies, high-throughput screening applications, and development of therapeutic strategies targeting epigenetic modifications. Compared to alternative methods such as CRISPR or RNA interference (RNAi), our knockout cell lines offer a stable, genetically altered cellular system that reduces variability and enhances reproducibility throughout experiments.

For researchers and clinicians focused on genetics, cell biology, or drug development, JMJD6 Gene Knockout Cell Lines represent a critical asset. They allow for precise investigations into gene function, providing insights that could lead to novel therapeutic avenues. Our commitment to quality and innovation in producing biological research tools makes us a trusted partner in advancing scientific discoveries. We meticulously generate our products to ensure reliability, performance, and convenience for our users.

Please note that all services are for research use only. Not intended for any clinical use.

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