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ITPK1 Knockout Cell Lines

Gene: ITPK1

Official Full Name: inositol-tetrakisphosphate 1-kinaseprovided by HGNC

Gene Summary: This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07820 ITPK1 Knockout cell line (HeLa) Human ITPK1 1:3~1:6 Negative Online Inquiry
KO07821 ITPK1 Knockout cell line (HCT 116) Human ITPK1 1:2~1:4 Negative Online Inquiry
KO07822 ITPK1 Knockout cell line (HEK293) Human ITPK1 1:3~1:6 Negative Online Inquiry
KO07823 ITPK1 Knockout cell line (A549) Human ITPK1 1:3~1:4 Negative Online Inquiry

Background

ITPK1 Gene Knockout Cell Lines are specifically engineered cell lines that have undergone targeted gene disruption to inactivate the inositol 1,3,4,5-tetraphosphate 5-kinase 1 (ITPK1) gene. This biological tool is pivotal for researchers investigating the roles of ITPK1 in cellular signaling pathways, particularly those involving inositol phosphates, which serve as essential messengers in various biological processes.

The key function of ITPK1 is to regulate the synthesis of inositol polyphosphates, which are critical in signaling cascades influencing cellular proliferation, differentiation, and metabolism. By knocking out the ITPK1 gene, researchers can elucidate the specific pathways and mechanisms that rely on this enzyme, allowing for a deeper understanding of its functions in both normal and pathological states.

The scientific importance of ITPK1 Gene Knockout Cell Lines extends into numerous research and clinical applications, particularly in the fields of cancer biology, neurobiology, and metabolic disorders. These cell lines offer invaluable insight into ITPK1’s involvement in disease mechanisms and can be used in high-throughput screening for potential therapeutic targets or drug efficacy studies.

Compared to conventional treatment or cell line options, ITPK1 Gene Knockout Cell Lines provide a unique advantage by offering a clear and precise model to study the effects of ITPK1 absence, enabling researchers to avoid confounding results associated with partial inhibition or non-specific effects. This specificity enhances data reliability and reproducibility, critical parameters in scientific research.

For researchers and clinicians seeking innovative solutions to advance their studies, the ITPK1 Gene Knockout Cell Lines offer unparalleled value by enabling a targeted approach to gene function analysis. Our company, with its extensive portfolio of genetically modified cell lines and commitment to advancing biological research, stands ready to support your inquiry into the complexities of cellular signaling and genetic regulation.

Please note that all services are for research use only. Not intended for any clinical use.

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