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ISYNA1 Knockout Cell Lines

Gene: ISYNA1

Official Full Name: inositol-3-phosphate synthase 1provided by HGNC

Gene Summary: This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03342 ISYNA1 Knockout cell line (HeLa) Human ISYNA1 1:3~1:6 Negative Online Inquiry
KO03343 ISYNA1 Knockout cell line (HCT 116) Human ISYNA1 1:2~1:4 Negative Online Inquiry
KO03344 ISYNA1 Knockout cell line (HEK293) Human ISYNA1 1:3~1:6 Negative Online Inquiry
KO03345 ISYNA1 Knockout cell line (A549) Human ISYNA1 1:3~1:4 Negative Online Inquiry

Background

ISYNA1 Gene Knockout Cell Lines are genetically engineered models designed to facilitate in-depth studies of the ISYNA1 gene, crucial for the biosynthesis of inositol phosphates, which play significant roles in cellular signaling and metabolic regulation. These cell lines have been meticulously developed using CRISPR-Cas9 technology to achieve complete knockout of the ISYNA1 gene, enabling researchers to investigate the phenotypic consequences of disrupted inositol phosphate metabolism.

The primary function of these knockout cell lines is to provide a controlled environment for examining the downstream effects of ISYNA1 loss on cellular processes, including proliferation, apoptosis, and responses to external stimuli. By comparing these knockout cells to their wild-type counterparts, researchers can elucidate the pathway alterations linked to ISYNA1 deficiency and clarify its role in various diseases, including cancer and metabolic syndromes.

From a scientific perspective, these cell lines are invaluable tools in both fundamental research and translational medicine. They open avenues for understanding the underlying mechanisms of inositol-related pathologies, thereby informing potential therapeutic strategies. In clinical settings, ISYNA1 knockout models can be leveraged for drug testing, biomarker discovery, and investigating disease pathology.

What sets our ISYNA1 Gene Knockout Cell Lines apart is the precision of gene editing, resulting in consistent and reproducible phenotypic outcomes. Additionally, every cell line is validated for quality and performance, ensuring reliable data generation, which is crucial for significant academic and biotech research projects.

For researchers and clinicians, these knockout cell lines represent a unique opportunity to explore novel hypotheses around inositol metabolism. Our company is deeply committed to advancing scientific discovery and provides unparalleled support and expertise in genetic model development, ensuring that you have the tools you need to drive your research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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