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IRF2BP2 Knockout Cell Lines

Gene: IRF2BP2

Official Full Name: interferon regulatory factor 2 binding protein 2provided by HGNC

Gene Summary: This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16885 IRF2BP2 Knockout cell line (HeLa) Human IRF2BP2 1:3~1:6 Negative Online Inquiry
KO16886 IRF2BP2 Knockout cell line (HCT 116) Human IRF2BP2 1:2~1:4 Negative Online Inquiry
KO16887 IRF2BP2 Knockout cell line (HEK293) Human IRF2BP2 1:3~1:6 Negative Online Inquiry
KO16888 IRF2BP2 Knockout cell line (A549) Human IRF2BP2 1:3~1:4 Negative Online Inquiry

Background

IRF2BP2 Gene Knockout Cell Lines represent a pioneering tool in molecular biology, specifically designed for studying the functional impact of IRF2BP2, a critical transcriptional regulator involved in various cellular processes, including immune response and inflammation. These cell lines are engineered to harbor intentional deletions of the IRF2BP2 gene, facilitating in-depth analyses of its biological roles and downstream effects on gene expression, cell signaling pathways, and cellular behavior.

The key mechanism of action of these knockout cell lines lies in the loss of IRF2BP2 protein activity, which traditionally serves to modulate transcriptional responses to various stimuli. By knocking out this gene, researchers can observe alterations in cellular responses to cytokines, growth factors, and other modulators of cellular physiology. This ability to manipulate and study signaling pathways provides valuable insights into IRF2BP2’s role in health and disease, particularly in contexts such as cancer, autoimmune disorders, and infectious diseases.

Scientifically, these cell lines hold significant importance in both research and clinical applications. They offer a robust platform for elucidating the role of IRF2BP2 in tumorigenesis and immune regulation, therefore serving as potential models for drug discovery and therapeutic intervention strategies. Their application extends to high-throughput screening and the development of targeted therapies aimed at modulating IRF2BP2-related pathways.

One of the unique selling points of IRF2BP2 Gene Knockout Cell Lines is their precision and reliability. Unlike traditional methods that may involve more complex genetic edits or non-specific knockdowns, these cell lines provide a clean and stable model for studying the specific effects of gene loss. They are also validated for consistent performance across multiple experiments, reducing variability and increasing reproducibility in research findings.

For researchers and clinicians alike, the value of IRF2BP2 Gene Knockout Cell Lines is evident. They empower scientists to delve deeper into the nuanced roles of IRF2BP2, potentially leading to groundbreaking discoveries in target validation and biomarker identification. Furthermore, they promote a better understanding of cellular mechanisms which could inform the development of novel therapeutic strategies.

Our company is dedicated to advancing scientific research through high-quality biological products. With a strong foundation in genetic engineering and cell line development, we are committed to offering innovative tools that enhance the efficiency and effectiveness of research efforts in molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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