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INPP4A Knockout Cell Lines

Gene: INPP4A

Official Full Name: inositol polyphosphate-4-phosphatase type I Aprovided by HGNC

Gene Summary: This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07895 INPP4A Knockout cell line (HeLa) Human INPP4A 1:3~1:6 Negative Online Inquiry
KO07896 INPP4A Knockout cell line (HCT 116) Human INPP4A 1:2~1:4 Negative Online Inquiry
KO07897 INPP4A Knockout cell line (HEK293) Human INPP4A 1:3~1:6 Negative Online Inquiry
KO07898 INPP4A Knockout cell line (A549) Human INPP4A 1:3~1:4 Negative Online Inquiry

Background

INPP4A Gene Knockout Cell Lines are advanced biological models engineered to lack the enzyme Inositol Polyphosphate-4-Phosphatase A (INPP4A), which is integral to the phosphoinositide signaling pathway. This gene knockout allows researchers to study the downstream effects of INPP4A loss, enabling the exploration of cellular processes such as proliferation, differentiation, and apoptosis that are influenced by inositol phosphates.

These cell lines function as valuable tools for dissecting the roles of INPP4A in various biological contexts, particularly its involvement in cellular signaling and metabolic pathways. By utilizing these cell lines, researchers can effectively simulate in vivo conditions to investigate the molecular mechanisms that may contribute to diseases such as cancer, neurodegeneration, and metabolic disorders. The knockout of this gene facilitates the assessment of changes in cellular behaviors and lipid signaling that could elucidate therapeutic targets.

The scientific importance of INPP4A Gene Knockout Cell Lines lies in their capacity to produce reproducible and quantifiable results, fostering breakthroughs in both basic and applied research. Their applications extend to drug discovery, where understanding the role of INPP4A can lead to the identification of novel pharmacological interventions. Compared to other alternatives, these knockout cell lines provide a specific and targeted approach to studying phosphoinositide metabolism without the complications introduced by partial inhibition or overexpression of the target gene.

Researchers and clinicians will find immense value in these cell lines not only for their specific applications but also for their ability to enhance the understanding of disease mechanisms at the molecular level. This product promises to accelerate translational research and discovery, offering critical insights that could lead to innovative treatment options.

Our company specializes in the development of high-quality biological products, leveraging cutting-edge technologies and in-depth expertise to support the scientific community in their quest for knowledge. With INPP4A Gene Knockout Cell Lines, we provide a robust resource designed to empower researchers in their investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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