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IGSF8 Knockout Cell Lines

Gene: IGSF8

Official Full Name: immunoglobulin superfamily member 8provided by HGNC

Gene Summary: This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22274 IGSF8 Knockout cell line (HeLa) Human IGSF8 1:3~1:6 Negative Online Inquiry
KO22275 IGSF8 Knockout cell line (HCT 116) Human IGSF8 1:2~1:4 Negative Online Inquiry
KO22276 IGSF8 Knockout cell line (HEK293) Human IGSF8 1:3~1:6 Negative Online Inquiry
KO22277 IGSF8 Knockout cell line (A549) Human IGSF8 1:3~1:4 Negative Online Inquiry

Background

IGSF8 Gene Knockout Cell Lines are genetically modified cell lines that have undergone precise deletion of the IGSF8 (Immunoglobulin Superfamily Member 8) gene. This product is designed for researchers exploring the functional roles of IGSF8 in various biological processes, including cellular adhesion, signaling pathways, and immune responses. By generating these knockout models, scientists can elucidate the phenotypic consequences of IGSF8 absence, enabling a detailed understanding of its contributions in physiological and pathological contexts.

The primary mechanism of action for the IGSF8 Gene Knockout Cell Lines involves the disruption of the IGSF8 gene using CRISPR/Cas9 technology or similar genome-editing approaches. This interruption leads to the loss of normal gene expression and function, allowing researchers to observe changes in cellular characteristics such as proliferation, migration, and differentiation. These models are invaluable for studying the role of IGSF8 in immune system regulation and its impact on diseases, including cancers and autoimmunity, thereby holding significant implications for therapeutic strategies.

From a scientific standpoint, the applications of IGSF8 Gene Knockout Cell Lines extend into both basic and translational research. They serve as essential tools for drug discovery, biomarker identification, and the development of novel immunotherapies. Moreover, these cell lines can significantly streamline experimental workflows, providing reliable, reproducible results that are critical in the competitive landscape of biomedical research.

Unlike traditional knockout models, which can be labor-intensive and time-consuming to create, our IGSF8 Gene Knockout Cell Lines are readily available and validated for immediate use, saving researchers valuable time and resources. Additionally, these cell lines offer superior consistency and fidelity due to the precision of modern gene-editing technologies.

At our company, we pride ourselves on delivering cutting-edge biological products backed by robust scientific expertise and a commitment to advancing knowledge in the life sciences. By choosing IGSF8 Gene Knockout Cell Lines, researchers and clinicians are not only obtaining high-quality experimental tools but also gaining access to innovative solutions that can propel their work forward in understanding and combating complex diseases.

Please note that all services are for research use only. Not intended for any clinical use.

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