Gene: IGSF11
Official Full Name: immunoglobulin superfamily member 11provided by HGNC
Gene Summary: IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21818 | IGSF11 Knockout cell line (A549) | Human | IGSF11 | 1:3~1:4 | Negative | Online Inquiry |
IGSF11 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to investigate the function of the immunoglobulin superfamily member 11 (IGSF11) gene. These cell lines are engineered using CRISPR-Cas9 technology to create targeted deletions of the IGSF11 gene, allowing for detailed studies on its role in cellular signaling and interaction, as well as its implications in immune response and cancer biology.
The primary function of IGSF11 is to mediate intercellular adhesion and signaling pathways that are critical for maintaining immune homeostasis. By knocking out this gene, researchers can elucidate the mechanisms by which IGSF11 contributes to various physiological processes, such as lymphocyte activation and differentiation. The resulting knockout cell lines serve as invaluable tools for exploring the downstream effects of IGSF11 disruption, giving insights into potential therapeutic targets in autoimmune diseases and malignancies.
Scientifically, the availability of these knockout cell lines is pivotal in both research and clinical settings. They facilitate high-throughput screening for drug discovery, enabling the identification of compounds that can modulate immune functions or correct deficiencies caused by IGSF11 mutations. Additionally, these cell lines can enhance the understanding of tumor immunology, aiding in the development of more effective immunotherapies.
In comparison to other genetic tools, IGSF11 Gene Knockout Cell Lines offer specificity and reproducibility, minimizing off-target effects commonly associated with traditional gene-editing techniques. Researchers benefit from well-characterized models that provide robust data for experimental reproducibility and validation.
The value of IGSF11 Gene Knockout Cell Lines lies in their ability to unlock novel biochemical pathways and enhance our understanding of immune system complexities. For researchers and clinicians pursuing advancements in immunology and oncology, these cell lines represent a critical asset in their investigative arsenal. Our company, with extensive experience in genetic engineering and cellular model development, is dedicated to providing high-quality biological products that empower scientific discovery and innovative research.
Please note that all services are for research use only. Not intended for any clinical use.
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