Gene: IFT56
Official Full Name: intraflagellar transport 56provided by HGNC
Gene Summary: Predicted to enable intraciliary transport particle B binding activity. Involved in cilium assembly. Located in cilium. Part of intraciliary transport particle B. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17006 | IFT56 Knockout cell line (HeLa) | Human | IFT56 | 1:3~1:6 | Negative | Online Inquiry |
KO17007 | IFT56 Knockout cell line (HCT 116) | Human | IFT56 | 1:2~1:4 | Negative | Online Inquiry |
KO17008 | IFT56 Knockout cell line (HEK293) | Human | IFT56 | 1:3~1:6 | Negative | Online Inquiry |
KO17009 | IFT56 Knockout cell line (A549) | Human | IFT56 | 1:3~1:4 | Negative | Online Inquiry |
IFT56 Gene Knockout Cell Lines are precisely engineered cellular models that lack the IFT56 gene, a critical component involved in intraflagellar transport (IFT) processes essential for ciliary and flagellar function. This innovative product enables researchers to explore the specific biological roles of the IFT56 gene in cellular locomotion and signaling pathways associated with ciliary defects, which can lead to various human diseases, including ciliopathies.
The functionality of IFT56 Gene Knockout Cell Lines lies in the complete absence of IFT56 protein, allowing scientists to study the consequences of its loss and how it affects key cellular mechanisms. By creating these knockout models using CRISPR-Cas9 technology, researchers can assess changes in cell morphology, migration patterns, and signaling pathways that rely on proper ciliary function. These cell lines serve as a robust framework for elucidating the molecular underpinnings of ciliary biogenesis and maintenance, providing critical insights that advance the field of cell biology and genetics.
The scientific importance of IFT56 Gene Knockout Cell Lines extends to both research and clinical applications, facilitating drug discovery processes and enabling the investigation of therapeutic strategies targeted at ciliopathies. By utilizing these cell lines, researchers can model disease states more accurately, enhancing the translatability of findings to potential clinical interventions.
What sets IFT56 Gene Knockout Cell Lines apart from alternative models is their precise genetic alteration validated through extensive genotyping and functional assays, ensuring reliability for high-quality research outcomes. Additionally, the availability of these cell lines in various backgrounds allows for tailored experiments that address specific research questions, making them versatile tools in the laboratory.
For researchers and clinicians seeking a deeper understanding of ciliary dysfunction and its implications in health and disease, IFT56 Gene Knockout Cell Lines are invaluable resources. They not only streamline experimental workflows but also pave the way for breakthroughs in the understanding of cilia-related disorders. Our company is dedicated to providing top-tier biological products grounded in rigorous scientific principles, ensuring that our offerings meet the highest standards necessary for impactful research and advancements in medical science.
Please note that all services are for research use only. Not intended for any clinical use.
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